Therapeutic applications of computer models of brain activity for Alzheimer disease.

Duch, Prof Wlodzislaw (2000) Therapeutic applications of computer models of brain activity for Alzheimer disease. [Conference Paper]

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Item Type:Conference Paper
Keywords:Neural models, Alzheimer disease, synaptic deletion, compensation, rehabilitiation
Subjects:Neuroscience > Neuropsychology
Computer Science > Dynamical Systems
Neuroscience > Neural Modelling
Biology > Theoretical Biology
ID Code:3320
Deposited By: Duch, Prof Wlodzislaw
Deposited On:18 Dec 2003
Last Modified:11 Mar 2011 08:55

References in Article

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[1] AMIT D.J., BRUNEL N., Dynamics of a recurrent network of spiking neurons before and following learning. Network, Vol. 8, pp. 373-404, 1997.

[2] BANQUET J.P, GAUSSIER P, CONTRERAS-VIDAL J.L, GISSLER A, BURNOD Y, LONG D.L., A neural model of memory, amnesia and cortico-hippocampal interactions. In [18], pp. 77-120, 1998.

[3] CALLAWAY E, HALLIDAY R, NAYLOR H, YANO L, HERZIG K., Drugs and human information processing. Neuro-psychopharmacology, Vol. 10, pp. 9-19, 1994.

[4] CRISWELL, E., Biofeedback and Somatics. Freeperson Press, Novato, USA, 1995.

[5] DAMASIO A.R., Descartes' Error: Emotion, Reason and the Human Brain. Papermac, 1996.

[6] DUCH W., Platonic model of mind as an approximation to neurodynamics. In: Brain-like computing and intelligent information systems, eds. S-i. Amari, N. Kasabov (Springer, Singapore), chap. 20, pp. 491-512, 1997.

[7] DUCH W., Sieci neuronowe w modelowaniu zaburzeń neuropsychologicznych i chorób psychicznych. Biocyberne-tyka 2000, Tom 6: Sieci neuronowe (eds. W. Duch, J. Korbicz, L. Rutkowski i R. Tadeusiewicz), chap. II.18, pp. 589-616, 2000.

[8] FUSI S., DEL GIUDICE P., AMIT D.J., Neurophysiology of a VLSI spiking neural network: LANN21, NALS group preprint, Univ. Of Rome, 1999,

[9] HASSELMO M.E., Runaway synaptic modification in models of cortex: Implications for Alzheimer's disease. Neural Networks, Vol. 7, pp.13-40, 1991.

[10] HASSELMO M.E., A computational model of the progression of Alzheimer's disease. MD Computing, Vol. 14, pp. 181-191, 1997.

[11] HORN D, LEVY N, RUPPIN E., Neuronal-based synaptic compensation: A computational study in Alzheimer's dis-ease. Neural Computation, Vol. 8, pp. 1227-1243, 1996.

[12] HORN, D, RUPPIN, E., USHER, M., HERRMANN, M., Neural network modeling of memory deterioration in Alz-heimer's disease. Neural Computation, Vol. 5, pp. 736-749, 1993.

[13] MAASS W, BISHOP C., Pulsed Neural Networks. MIT Press, Bradford Book, Cambridge, MA, 1999.

[14] MCCLELLAND J. L., RUMELHART D.E., eds. Parallel distributed processing: Explorations in the microstructure of cognition, Vol. I, II, MIT Press, Cambridge, MA, 1987.

[15] MCCLELLAND, J.L., MCNAUGHTON, B.L., O'REILLY, R.C., Why there are complementary learning systems in the hippocampus and neocortex: insights from the successes and failures of connectionist models of learning and memory. Psychological Review, Vol. 102, pp. 419-457, 1995.

[16] MURRE J. M., TraceLink: A model of amnesia and consolidation of memory. Hippocampus, Vol. 6, pp. 675-684, 1996.

[17] MURRE J. M., Implicit and explicit memory in amnesia: some explanations and predictions by the TraceLink model. Memory, Vol. 5, pp. 213-232, 1997.

[18] PARKS R.W, LEVINE D.S, LONG D, eds. Fundamentals of Neural Network Modeling. MIT Press, Cambridge, MA, 1998.


[20] ROMERO B., Self-Maintenance-Therapy (SMT) in early Alzheimer Disease. European Archives of Psychiatry and Clinical Neuroscience, Vol. 248, pp.13-14, 1998.

[21] REGGIA J. A, RUPPIN E, BERNDT R.S, eds. Neural Modeling of Brain and Cognitive Disorders. World Scientific, 1996.

[22] REGGIA J, GOODALL S, CHEN Y, RUPPIN E, WHITNEY C., Modeling Post-Stroke Cortical Map Reorganization. In [21], pp. 283-302, 1996.

[23] RUPPIN E, Neural Modeling of Psychiatric Disorders. Network, Vol. 6, pp. 635-656, 1995

[24] RUPPIN E, HORN D, LEVY N, REGGIA J., Computational Studies of Synaptic Alterations in Alzheimer's Disease. In: J. REGGIA, E. RUPPIN, and R. BERNDT, Eds., Neural Modeling of Brain and Cognitive Disorders, World Scientific, 1996.

[25] RUPPIN, E, REGGIA, J., A neural model of memory impairment in diffuse cerebral atrophy. British Journal of Psy-chiatry Vol. 166, pp. 19-28, 1995.

[26] SPITZER M., Phantom Limbs, Self-Organizing Feature Maps, and Noise-Driven Neuroplasticity. In [21], pp. 273-282, 1996.

[27] XING J, GERSTEIN G.L, Networks with lateral connectivity. I. Dynamic properties mediated by the balance of in-trinsic excitation and inhibition. II. Development of neuronal grouping and corresponding receptive field changes. III. Plasticity and reorganization of somato-sensory cortex. J. Neurophysiology, Vol. 75, pp. 184-232, 1996.


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