Rate-Control or Rhythm-Contol: Where do we stand?

L, Testa and G, Trotta and A, Dello Russo and M, Casella and G, Pelargonio and F, Andreotti and F, Bellocci (2005) Rate-Control or Rhythm-Contol: Where do we stand? [Journal (Paginated)]

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Atrial fibrillation is the most common sustained rhythm disturbance and its prevalence is increasing worldwide due to the progressive aging of the population. Current guidelines clearly depict the gold standard management of acute symptomatic atrial fibrillation but the best-long term approach for first or recurrent atrial fibrillation is still debated with regard to quality of life, risk of new hospitalizations, and possible disabling complications, such as thromboembolic stroke, major bleeds and death. Some authors propose that regaining sinus rhythm in all cases, thus re-establishing a physiologic cardiac function not requiring a prolonged antithrombotic therapy, avoids the threat of intracranial or extracranial haemorrhages due to Vitamin K antagonists or aspirin. On the contrary, advocates of a rate control approach with an accurate antithrombotic prophylaxis propose that such a strategy may avoid the risk of cardiovascular and non cardiovascular side effects related to antiarrhythmic drugs. This review aims to explore the state of our knowledge in order to summarize evidences and issues that need to be furthermore clarified.

Item Type:Journal (Paginated)
Keywords:atrial fibrillation, rate control, rhythm control, secondary prevention
Subjects:JOURNALS > Indian Pacing and Electrophysiology Journal
ID Code:4596
Deposited By: Indian Pacing and Electrophysiology, Journal
Deposited On:12 Nov 2005
Last Modified:11 Mar 2011 08:56

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