Gouri, Ms Anahita and Sathe, Ms Kinneri and Ramachandran, Dr Hema and Rajadhyaksha, Dr Medha (2004) Effect of lithium on acetylcholine esterase activity, and isozyme pattern in developing chick brain. [Conference Poster] (Unpublished)
Full text available as:
|
PDF
43Kb |
Abstract
Acetylcholine Esterase is an enzyme, which hydrolyses acetylcholine and is used as a marker for cholinergic neural function. It is known to be involved in synaptogenesis. While on one hand it is known to be a marker for the developing chick brain it is also implicated in neurodegenerative diseases. In vertebrates the protein is synthesized by a single gene and undergoes alternative splicing to give 6-8 isoforms. Isozyme patterns of acetylcholine esterase have been suggested to be useful prognostic markers of neuronal degeneration. Lithium a well-known teratogen is known to induce apoptosis in the developing chick brain. Understanding the dynamics of acetylcholine esterase isoform pattern in lithium induced neural tissue damage would help elucidating the role of these isoforms in frank neurodegenerative diseases. We have therefore studied activity and isozyme pattern of acetylcholine esterase in lithium treated and control 7 day old developing chick brain and report the same.
Item Type: | Conference Poster |
---|---|
Additional Information: | A platform presentation was delivered at the “ Joint International Neuroscience Conference” held in May 2004, at the university of Hyderabad. The author was honoured with the ‘D.M Kar - Young scientist 2004 award’. This project also received the 'Lady Tata Memorial Trust’ scholarship. |
Keywords: | Anahita Gouri, Acetylcholinesterase, Lithium Chloride, Invertebrate AChE, Vertebrate AChE, developing chick brain |
Subjects: | Neuroscience > Neurochemistry |
ID Code: | 4668 |
Deposited By: | Gouri, Ms Anahita |
Deposited On: | 30 Dec 2005 |
Last Modified: | 11 Mar 2011 08:56 |
References in Article
Select the SEEK icon to attempt to find the referenced article. If it does not appear to be in cogprints you will be forwarded to the paracite service. Poorly formated references will probably not work.
Metadata
- ASCII Citation
- Atom
- BibTeX
- Dublin Core
- EP3 XML
- EPrints Application Profile (experimental)
- EndNote
- HTML Citation
- ID Plus Text Citation
- JSON
- METS
- MODS
- MPEG-21 DIDL
- OpenURL ContextObject
- OpenURL ContextObject in Span
- RDF+N-Triples
- RDF+N3
- RDF+XML
- Refer
- Reference Manager
- Search Data Dump
- Simple Metadata
- YAML
Repository Staff Only: item control page