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Oncogenic Potential of Radiofrequecy Emissions for Mobile Phones

Goyal, S and Sagoo, HS and Pramod, J (2009) Oncogenic Potential of Radiofrequecy Emissions for Mobile Phones. [Journal (On-line/Unpaginated)]

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Abstract

With the advent of the rising telecom industry there is growth in the usage of the mobile phones by manifold and when we are in country like India, in order to cover one billion population, several transmission towers have been installed to create a jungle of such masts rising atop many buildings in the densely populated parts of India. The erection of these towers has lead to speculations that there may be increased incidence of cancer after exposure to the RF emissions from mobile telephone base stations. There are no high-quality epidemiologic studies that can be used to evaluate health risks from RF exposure. Laboratory studies in this area have been somewhat confusing. Some animal studies suggest that RF fields accelerate the development of sarcoma colonies in the lung, mammary tumors, skin tumors, hepatomas, and sarcomas. In contrast, other studies conducted on large scale on the cell lineage and people working in areas with high RF emissions have not found carcinogenic effects. These conflicting results indicate the need for more well-conducted studies. This paper provides a review of the laboratory studies and indicates what conclusions about RF-induced cancer can be drawn.

Item Type:Journal (On-line/Unpaginated)
Keywords:Radiofrequency fields, Cancer, Health effects, Laboratory studies, Mobile phones
Subjects:JOURNALS > Online Journal of Health and Allied Sciences
ID Code:6958
Deposited By: Kakkilaya Bevinje, Dr. Srinivas
Deposited On:13 Sep 2010 03:56
Last Modified:11 Mar 2011 08:57

References in Article

Select the SEEK icon to attempt to find the referenced article. If it does not appear to be in cogprints you will be forwarded to the paracite service. Poorly formated references will probably not work.

1. Kuster N, Balzano Q, Lin J ( Eds.) (1997) Mobile Communication Safety. New York: Chapman and Hall.

2. Scaiano JC, Cozens FL, McLean J. Model for the rationalization of magnetic field effects in vivo Application of the radical-pair mechanism to biological systems. Photochem Photobiol .1994 Jun 59; 6:585-589.

3. Brocklehurst B, McLauchlan KA .Free radical mechanism for the effects of environmental electromagnetic fields on biological systems. Int J Radiat Biol. 1996 Jan; 69(1):3-24.

4. Mild KH, Hardell L, Carlberg M .Pooled analysis of two Swedish case-control studies on the use of mobile and cordless telephones and the risk of brain tumours diagnosed during 1997-2003. Int J Occup Saf Ergon .2007 ; 13(1):63-71.

5. Hardell L, Carlberg M, Hansson Mild K. Pooled analysis of two case-control studies on use of cellular and cordless telephones and the risk for malignant brain tumours diagnosed in 1997-2003. Int Arch Occup Environ Health .2006 ; 79:630-639.

6. Hardell L, Mild KH, Carlberg M, Söderqvist F. Tumour risk associated with use of cellular telephones or cordless desktop telephones. World J Surg Oncol. 2006; 4:74.

7. Kan P, Simonsen SE, Lyon JL, Kestle JR.Cellular phone use and brain tumor: a meta-analysis. J Neurooncol .2008; 86:71-78.

8. Hardell L, Carlberg M, Söderqvist F, Hansson Mild K. Meta-analysis of long-term mobile phone use and the association with brain tumours. Int J Oncol .2008; 32:1097-1103.

9. Sadetzki S, Chetrit A, Jarus-Hakak A, Cardis E, Deutch Y, Duvdevani S. Cellular phone use and risk of benign and malignant parotid gland tumors—a nationwide case-control study. American J Epidemiology .2008; 167:457-67.

10. Reiter R J. Pineal melatonin: cell biology of its synthesis and of its physiological interactions. Endocrinology Review .1991; 12(2):151.

11. NRC (National Research Council) .Possible Health Effects of Exposure to Residential Electric and Magnetic Fields. Washington DC, National Academy Press. 1997

12. NIEHS (National Institute of Environmental Health Sciences).Working Group Report. Assessment of the Health Effects from Exposure to Power-line Frequency Electric and Magnetic Fields (C J Porter and M S Wolfe, Eds).Research Triangle Park, NC, US National Institutes of Health.1998;NIH Publication No. 98-3981: 311.

13. Stevens R G.Electric power use and breast cancer: a hypothesis.American J Epidemiology .1987 ; 125:556.

14. Stark K D C, Krebs T, Altpeter E, Manz B, Griot C and Abelin T. Absence of chronic effect of exposure to short-wave radio broadcast signal on salivary melatonin concentrations in dairy cattle. J Pineal Research. 1997; 22:171.

15. Vollrath L, Spessert R, Kratzsch T, Keiner M and Hollmann H. No short-term effects of high frequency electromagnetic fields on the mammalian pineal gland. Bioelectromagnetics .1997; 18:376.

16. Byus CV, Pieper SE, Adey WR.The effects of low-energy 60-Hz environmental electromagnetic fields upon the growth-related enzyme ornithine decarboxylase. Carcinogenesis .1987 Oct 8; 10:1385-1389.

17. Byus CV, Kartun K, Pieper S, Adey WR. Increased ornithine decarboxylase activity in cultured cells exposed to low energy modulated microwave fields and phorbol ester tumor promoters.Cancer Research .1988 Aug 1; 48(15):4222-4226.

18. Lai H and Singh N P. Acute low-intensity microwave exposure increases DNA single-strand breaks in rat brain cells.Bioelectromagnetics .1995; 16:207.

19. Lai H and Singh N P. Single- and double-strand DNA breaks in rat brain cells after acute exposure to radiofrequency electromagnetic radiation. Int J Radiat Biology. 1996; 69: 513.

20. Lai H and Singh NP. Acute exposure to a 60 Hz magnetic field increases DNA strand breaks in rat brain cells. Bioelectromagnetics.1997; 18:156-165.

21. Khalil A M, Qassem W F and Suleiman M M . A preliminary study on the radiofrequency field-induced cytogenetic effects in cultured human lymphocytes. Dirasat.1993; 20:121.

22. Garaj-Vrhovac V, Horvat D and Koren Z. Comparison of chromosome aberration and micronucleus induction in human lymphocytes after occupational exposure to vinyl chloride monomer and microwave radiation. Periodicum Biologorium.1990b; 92: 411.

23. Balcer-Kubiczek E K and Harrison G H. Evidence for microwave carcinogenesis in vitro. Carcinogenesis.1985; 6:859.

24. Balcer-Kubiczek E K and Harrison G H. Neoplastic transformation of C3H/10T1/2 cells following exposure to 120-Hz modulated 2.45 GHz microwaves and phorbol ester tumor promoter. Radiat Res.1991;126:65.

25. Scarfì M R, Lioi M B, d’Ambrosio G, Massa R, Zeni O, De Pietro R and De Berardino D. Genotoxic effects of mitomycin-C and microwave radiation on bovine lymphocytes. Electro-Magnetobiology.1996;15:99.

26. Maes A, Collier M, Van Gorp U, Vandoninck S and Verschaeve L. Cytogenetic effects of 935.2-MHz (GSM) microwaves alone and in combination with mitomycin C. Mutat Research.1997; 393:151.

27. Lahkola A, Auvinen A, Raitanen J, Schoemaker MJ, Christensen HC, Feychting M, Johansen C, Klaeboe L, et al. Mobile phone use and risk of glioma in 5 North European countries. Int J Cancer.2007; 120(8):1769-1775.

28. Miyakoshi J, Takemasa K, Takashima Y, Ding GR, Hirose H, Koyama S. Effects of exposure to a 1950 MHz radio frequency field on expression of Hsp70 and Hsp27 in human glioma cells. Bioelectromagnetics.2005; 26:251-257.

29. Takebayashi T, Varsier N, Kikuchi Y, Wake K, Taki M, Watanabe S. Mobile phone use, exposure to radiofrequency electromagnetic field, and brain tumour: a case-control study. Br J Cancer.2008; 98:652-659.

30. Klaeboe L, Blaasaas KG, Tynes T. Use of mobile phones in Norway and risk of intracranial tumours. Euro J Cancer Prev.2007; 16:158-164.

31. Takebayashi T, Akiba S, Kikuchi Y, Taki M, Wake K, Watanabe S, Yamaguchi N. Mobile phone use and acoustic neuroma risk in Japan. Occup Environ Med.2006; 63:802-807.

32. Schüz J, Böhler E, Schlehofer B, Berg G, Schlaefer K,HettingerI.Radiofrequency electromagnetic fields emitted from base stations of DECT cordless phones and the risk of glioma and meningioma (Interphone Study Group, Germany). Radiat Res.2006; 166:116-119.

33. Lönn S, Ahlbom A, Hall P, Feychting M. Swedish Interphone Study Group. Long-term mobile phone use and brain tumor risk. Am J Epidemiology .2005; 161:526-535.

34. Röösli M, Michel G, Kuehni CE, Spoerri A. Cellular telephone use and time trends in brain tumour mortality in Switzerland from 1969 to 2002. Eur J Cancer Prev.2007; 16:77-82.

35. Muscat JE, Hinsvark M, Malkin M. Mobile telephones and rates of brain cancer. Neuroepidemiology.2006; 27:55-56.

36. Hardell L, Carlberg M, Ohlson CG, Westberg H, Eriksson M, Hansson Mild K. Use of cellular and cordless telephones and risk of testicular cancer. Int J Androl.2007; 30:115-122.

37. Linet MS, Taggart T, Severson RK, Cerhan JR, Cozen W, Hartge P, Colt J. Cellular telephones and non-Hodgkin lymphoma. Int J Cancer.2006; 119:2382-2388.

38. Lönn S, Ahlbom A, Christensen HC, Johansen C, Schüz J, Edström S, et al. Mobile phone use and risk of parotid gland tumor. Am J Epidemiology. 2006; 164:637-643.

39. H. Hirose et al. Bioelectromagnetics.2006; 27:494-504.

40. Sakuma N, Komatsubara Y, Takeda H, Hirose H, Sekijima M, Nojima T, Miyakoshi J. DNA strand breaks are not induced in human cells exposed to 2.1425 GHz band CW and W-CDMA modulated radiofrequency fields allocated to mobile radio base stations. Bioelectromagnetics .2005; 27(1):51-57.

41. Vijayalaxmi, N. Mohan, M. L. Meltz and M. A. Wittler . Proliferation and cytogenetic studies in human blood lymphocytes exposed in vitro to 2450-MHz radiofrequency radiation. Int. J. Radiat. Biol.1997; 72:751-757.

42. Maes A, Collier M, Slaets D and Verschaeve L. Cytogenetic effects of microwaves from mobile communication frequencies (954 MHz). Electro-Magnetobiology. 1995; 14: 91.

43. Dutta S K, Nelson W H, Blackman C F and Brusick D J. Lack of microbial genetic response to 2.45-GHz CW and 8.5- to 9.6-GHz pulsed microwaves. J Microwave Power Electromag Energy.1995; 14: 275.

44. Meltz M L, Walker K A and Erwin D N. Radiofrequency (microwave) radiation exposure of mammalian cells during UV-induced DNA repair synthesis. Radiat Res.1987; 110:255.

45. Meltz M L, Eagan P and Erwin D N. Proflavin and microwave radiation: absence of a mutagenic interaction. Bioelectromagnetics.1990; 11:149.

46. Phillips J L, Ivaschuk O, Ishida-Jones T, Jones R A, Campbell-Beachler M and Haggren W. DNA damage in Molt-4 T-lymphoblastoid cells exposed to cellular telephone radiofrequency fields in vitro. Bioelectrochem Bioenergetics.1998; 45:103.

47. Verschaeve L and Maes A. Genetic, carcinogenic and teratogenic effects of radiofrequency fields. Mutat Res .1998; 410:141.

48. Royal Society of Canada Expert Panel Report. A review of the potential health risks of radiofrequency fields from wireless telecommunication devices. An Expert Panel Report prepared at the request of the Royal Society of Canada for Health Canada. Ottawa, Royal Society of Canada;1999: RSC.EPR 99-1.

49. Vasquez M V, Clancy C J, Blackwell D B, Donner M D, Tice R T, Hook G H ,et al. Genotoxicity of radio frequency radiation fields generated from analog, TDMA, CDMA and PCNA in human blood cells evaluated using single gel (SCG) electrophoresis and the cytochalasin B micronucleus assay. Environ Mol Mutagen. 1999; 33(30):66.

50. Cain C D, Thomas D L and Adey W R. Focus formation of C3H/10T1/2 cells and exposure to a 836.55 MHz modulated radiofrequency field. Bioelectromagnetics.1997; 18:237.

51. Ciaravino V, Meltz M L and Erwin D N. Effects of radiofrequency radiation and simultaneous exposure with mitomycin C on the frequency of sister chromatid exchanges in Chinese hamster ovary cells. Environ Mutagen.1987; 9:393.

52. Ciaravino V, Meltz M L and Erwin D N.Absence of a synergistic effect between moderate-power radiofrequency electromagnetic radiation and Adriamycin on cell-cycle progression and sister-chromatid exchange. Bioelectromagnetics .1991; 12:289.

53. Meltz M L, Eagan P and Erwin D N. Absence of mutagenic interaction between microwaves and mitomycin C in mammalian cells. Environ Mol Mutagen.1989; 13: 294.

54. Meltz M L, Eagan P and Erwin D N. Proflavin and microwave radiation: absence of a mutagenic interaction. Bioelectromagnetics .1990; 11:149.

55. Kerbacher J J, Meltz M L and Erwin D N. Influence of radiofrequency radiation on chromosome aberrations in CHO cells and its interaction with DNA-damaging agents. Radiat Res .1990; 123, 311.

56. Wu R Y, Chiang H, Shao B J, Li N G and Fu Y D. Effects of 2.45 GHz microwave radiation and phorbol ester 12-O-tetradecanoylphorbol-13-acetate on dimethylhydrazine-induced colon cancer in mice. Bioelectromagnetics.1994; 15:531

57. Imaida K, Taki M, Yamaguchi T, Ito T, Watanabe S, Wake K, et al. Lack of promoting effects of the electromagnetic near-field used for cellular phones (929.2 MHz) on rat liver carcinogenesis in a medium-term liver bioassay. Carcinogenesis.1998a; 19, 311.

58. Imaida K, Taki M, Watanabe S-i, Kamimura Y, Ito T, Yamaguchi T, et al. The 1.5 GHz electromagnetic near-field used for cellular phones does not promote rat liver carcinogenesis in a medium term liver bioassay. Jpn J Cancer Res.1998b; 89, 995.

59. Inskip Peter D, Tarone Robert E, Hatch Elizabeth E. P, Timothy C. Wilcosky, William R. Shapiro, Robert G. Selker, et al. Cellular Telephone Use and Brain Tumors. The New England journal of Medicine.2001; 344(2):79-86.

60. Morgan RW, Kelsh MA, Zhao K, Exuzides KA, Heringer S, Negrete W. Radiofrequency exposure and mortality from cancer of brain and lymphocytes/hematopoietic systems. Epidemiology.2000; 11:118-127.

61. Health Physics Society. Cellular Phones and Base Stations. Available at http://hps.org/publicinformation/ate/faqs/cellphoneqa.html [accessed 7 October 2006].

62. Advisory Group on Non-Ionizing Radiation. Health Effects from Radiofrequency Electromagnetic Fields. Report of an Advisory Group on Non-ionizing Radiation. 2003; Documents of the NRPB 14(2): Advisory Group on Non-Ionizing Radiation. Available at http://www.hpa.org.uk/radiation/publications/documents_of_nrpb/abstracts/absd14-2.htm

63. Spalding JF, Freyman RW and Holland LM. Effects of 800- MHz electromagnetic radiation on body weight, activity, hematopoiesis and life span in mice. Health Phys.1971; 20, 421–424

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