Over the counter ophthalmic drug misuse, are we aware?

Kadri, R and Hegde, S and Kudva, AA and Achar, A (2010) Over the counter ophthalmic drug misuse, are we aware? [Journal (On-line/Unpaginated)]

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Aim: To investigate the misuse of ‘over the counter’ ophthalmic medications in our city. Method: Responses of a structured questionnaire covering various aspects of over the counter drug use was obtained from pharmacy workers in and around our city. Results: Eighty nine pharmacy workers took part in this cross–sectional study. An average number of seven patients per day with ophthalmic complaints were seen by the pharmacy workers. Dispensing over the counter was practiced by 89.9% of the pharmacists. The most common complaint of the patients visiting the pharmacy, was redness and itching (86.5%). Antibiotics (96.6%) were the most common eye drops dispensed over the counter, followed by steroids (55.1%), decongestants (54.1%), antibiotic-steroid combination eye drops (29.2%) and lubricants (16.8%). Awareness regarding complications of steroid use was seen in 40.6% of pharmacists. 6.7% pharmacists had seen patients with complications following use of over the counter medications. In our study, majority of the eye drops dispensed were prescription drugs. Conclusion: Availability of prescription eye drops over the counter is an immense public threat. Educating the pharmacist and the population can decrease ocular morbidity. Research into methods to effectively deal with over-the-counter drug misuse is required and law can be enforced based on the findings.

Item Type:Journal (On-line/Unpaginated)
Keywords:Over the counter, drug misuse, eye drops, pharmacy, non-prescription drugs
Subjects:JOURNALS > Online Journal of Health and Allied Sciences
ID Code:7010
Deposited By: Kakkilaya Bevinje, Dr. Srinivas
Deposited On:13 Sep 2010 03:51
Last Modified:11 Mar 2011 08:57

References in Article

Select the SEEK icon to attempt to find the referenced article. If it does not appear to be in cogprints you will be forwarded to the paracite service. Poorly formated references will probably not work.

1. Srinivasan S. OTC Drugs: Some Legal aspects. Bulletin of the Society for Rational Therapy. July 1991.

2. Francis PA. OPPI’s OTC Dream. June 22, 2005. Available at

3. Blenkinsopp A, Bradley C. Patients, Society and the increase in self medication. BMJ 1996 Mar 9;312 (7031):629-32.

4. OTC. Chloramphenicol eye drops, guidance. Available at

5. Encyclopedia - Eye Drops. Available at at

6. Sosa AB, Epstein SP, Asbell PA. Evaluation of toxicity of commercial ophthalmic fluoroquinolone antibiotics as assessed on immortalized corneal and conjunctival epithelial cells. Cornea 2008;27(8):930-4.

7. Red Eye: Approach to the ophthalmologic patient: Merck Manual Professional. Available at

8. Tayanithi P, Aramwit P. Self – medicated over the counter ophthalmic solutions in central Bangkok. J-Med Assoc Thai. 2005 Sep;88(Suppl 4):S330-4

9. Munjal VP, Dhir SP, Jain IS. Steroid induced glaucoma. Indian J Ophthalmol 1982;30(4):379-82

10. Tabbara KF. Blindness in the eastern Mediterranean countries. Br J Ophthalmol 2001;85:771–775

11. Thygeson P, Hogan MJ, Kimura SJ. The unfavourableeffect of topical steroid therapy on herpetic keratitis. Trans Am Ophthalmol Soc 1960;58:245-57.

12. Soparkar CN, Wilhelmus KR, Koch DD, Wallace GW, Jones DB. Acute and Chronic conjunctivitis due to over the counter ophthalmic decongestants. Arch Ophthalmol 1997 Jan;115(1):34–8.

13. Tappeiner C, Sarra GM, Abegg M. Abuse of Vasoconstrictive eyedrops mimicking an ocular pemphigoid. Eur J. Ophthalmol 2009 Jan–Feb;19(1):129–32.

14. Rumelt MB. Blindness from misuse of over – the counter eye medications. Ann opthalmol 1988 Jan;20(1):26-7, 30.

15. Berdy GJ, Abelson MB, Smith LM, George MA. Preservative – free artificial tear preparations: Assessment of corneal epithelial toxic effects. Arch ophthalmol 1992 Apr;110(4):528–32.

16. Avaki M, Yaguchi S, Iwasawa A, Koide R. Cytotoxicity of ophthalmic solutions with and without preservatives to human corneal endothelial cells, epithelial cells and conjunctival epithelial cells. Clin experiment ophthalmol 2008 Aug;36(6):553–9

17. Kim MS, Choi CY, Kim JM, Chang HR, Woo HY. Microbial contamination of multiply used preservative-free artificial tears packed in reclosable containers. Br J Ophthalmol. 2008 Nov;92(11):1518-21. Epub 2008 Sep 9

18. Are We Ready Yet? Drugs over the counter - An Indian Perspective. Accessed at

19. Satoskar RS. The expanding role of pharmacologists in the Changing Indian Scene J. Postgrad Med 1986;32(3):11–14


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