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A Study on Ajuga bracteosa wall ex. Benth for analgesic activity

Akriti Pal , RS Pawar, Int J Cur Bio Med Sci. (2011) A Study on Ajuga bracteosa wall ex. Benth for analgesic activity. [Journal (Paginated)]

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Abstract

Ethnopharmacological relevance: Ajuga bracteosa wall ex. Benth (Labiatae) is traditionally used medicine in the treatment of malaria and gout. The plant is substitute of cinchona. Its allied species Ajuga Parviflora is also found sporadically. In Ayurvedic prepration the aqueous extract of the leaves part showed diuretic activity. Aim of the study: The present study was carried out to investigate analgesic activity of Ajuga bracteosa wall ex. Benth aerial part extracts. Materials and methods: A. bracteosa, a widespread medicinal plant traditionally used in the disease, was collected from Hamirpur district of Himachal Pradesh. Aerial part was extracted with petroleum ether, chloroform, methanol, ethanol and water. Analgesic activity of these extracts was assessed in swiss albino mice with acetic acid-induced writhing test and tail immersion test. Results: At the doses used (200 and 400 mg/kg, i.p.) chloroform and water extracts showed significant and dose-dependent analgesic effects. Conclusion: Our results indicate that extracts Ajuga bracteosa wall ex. Benth obtained from demonstrate an analgesic effect probably mediated by opioid receptors.

Item Type:Journal (Paginated)
Keywords:Ajuga bracteosa, Analgesics, Tail immersion test, acetic acid-induce writhing test.
Subjects:JOURNALS
ID Code:7313
Deposited By: CurrentSciDirect Publications, International Journal of Current Biological and Medical Science (IJCBMS)
Deposited On:02 May 2011 15:53
Last Modified:02 May 2011 15:53

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