Cogprints

An uncommon subtype of breast carcinoma in a man: The pure mucinous carcinoma

Sawssen Dhambri , Mona Mlika , Aïda Ayadi-Kaddour , Abdelfattah Zeddini , Faouzi El Mezni , Int J Cur Biomed Phar Res. (2011) An uncommon subtype of breast carcinoma in a man: The pure mucinous carcinoma. [Journal (Paginated)]

Full text available as:

[img]
Preview
 PDF (An uncommon subtype of breast carcinoma in a man: The pure mucinous carcinoma) - Published Version
Available under License Creative Commons Attribution No Derivatives.
1374Kb

Abstract

Aim: Our purpose is to describe a new case of pure mucinous carcinoma in a man, to put emphasis on the rarity of this histologic subtype and the problems of management due to the fewer reported cases in the literature and to compare it with the female counterpart. Observation: We report the case of a 79- year-old man presenting as a nodular mass of the right breast. The clinical symptoms weren’t specific and the diagnosis was based on histological and immunohistochemical findings. Conclusion: Male breast carcinoma is rare compared to its female counterpart representing less than 2% of male breast carcinomas and 1% of all breast carcinomas. Pure mucinous carcinoma in male is an extremely rare histological subtype. It is a variety of carcinoma of the breast which is characterized by the production of an abundant extra-cellular and/or intra-cellular mucin. It has been regarded as one of the more benign forms of breast carcinomas. To our knowledge, about 30 cases of mucinous breast carcinoma in male have been reported in the English literature and only 10 cases of pure mucinous carcinoma have been described. In general, pure mucinous carcinomas have a favorable prognosis. Numerous studies have shown that breast carcinomas in male behave more aggressively compared to those in females. Further research is needed on male carcinomas as they are becoming more frequent.

Item Type:Journal (Paginated)
Keywords:Mucinous carcinoma, male breast carcinoma, pure mucinous type, prognosis.
Subjects:JOURNALS
ID Code:7332
Deposited By: CurrentSciDirect Publications, International Journal of Current Biomedical and Pharmaceutical Research (IJCBPR)
Deposited On:02 May 2011 12:12
Last Modified:02 May 2011 12:12

References in Article

Select the SEEK icon to attempt to find the referenced article. If it does not appear to be in cogprints you will be forwarded to the paracite service. Poorly formated references will probably not work.

[1] MartÃnez-Consuegra N, Baquera-Heredia J, Robles-Vidal C, Zumarán-Cuéllar O, Ortiz-Hidalgo C. [Pure mucinous (colloid) carcinoma of the male breast. An uncommon subtype]. Gac Med Mex. 2007;143(1):79-81.

[2] Wainwright JM .Carcinoma of the male breast. Ann Surg. 1927;14:836–857

[3] Kavalakat AJ, Covilakam RK, Culas TB. Secretory carcinoma of breast in a 17-year-old male. World J Surg Oncol. 2004; 2;2:17.

[4] Anan K, Mitsuyama S, Tamae K, Nishihara K, Iwashita T, Abe Y, Ihara T, Nakahara S, Katsumoto F, Toyoshima S. Pathological features of mucinous carcinoma of

[5] the breast are favourable for breast-conserving therapy. EJSO 2001; 27: 459–463

[6] Donegan WL, Redlich PN. Breast cancer in men. Surg Clin. 1927;76:343–363

[7] Giordano SH, Cohen DS, Buzdar AU, Perkins G, Hortobagyi GN. Breast carcinoma in men: a population-based study. Cancer 2004;101:51–57

[8] Peschos D, Tsanou E, Dallas P, Charalabopoulos K, Kanaris C, Batistatou A. Mucinous breast carcinoma presenting as Paget's disease of the nipple in a man: A case report. Diagn Pathol. 2008 Oct 24;3:42.

[9] Dragoumis DM, Assimaki AS, Tsiftsoglou AP. Pure mucinous carcinoma with axillary lymph node metastasis in a male breast. Breast Cancer. 2009;10.

[10] Martínez-Consuegra N, Baquera-Heredia J, Robles-Vidal C, Zumarán-Cuéllar O, Ortiz-Hidalgo C. [Pure mucinous (colloid) carcinoma of the male breast. An uncommon subtype]. Gac Med Mex. 2007;143(1):79-81.

[11] Adair JD, Harvey KP, Mahmood A, Caralis J, Gordon W, Yanish G. Recurrent pure mucinous carcinoma of the breast with mediastinal great vessel invasion: HER-2/neu confers aggressiveness. Am Surg. 2008;74(2):113-6.

[12] Dawson PJ, Paine TM, Wolman SR. Immunocytochemical characterization of male breast cancer. Mod Pathol 1992; 5:621–625.

[13] Fox SB, Day CA, Rogers S. Lack of c-erbB-2 oncoprotein expression in male breast carcinoma. J Clin Pathol 1991; 44:960–961

[14] Melamed MR, Robbins GF, Foote FW Jr. Prognostic significance of gelatinous mammary carcinoma. Cancer 1961; 14: 699–704.

[15] Diab SG, Clark GM, Osborne CK, Libby A, Allred DC, Elledge RM. Tumor characteristics and clinical outcome of tubular and mucinous breast carcinomas. J Clin Oncol 1999; 17: 1442–8.

[16] Park S, Kim JH, Koo J, Park BW, Lee KS. Clinicopathological characteristics of male breast cancer. Yonsei Med J. 2008 Dec 31;49(6):978-86.

Metadata

Repository Staff Only: item control page

Cogprints is powered by EPrints 3 which is developed by the School of Electronics and Computer Science at the University of Southampton. More information and software credits.