Insular Carcinoma of Thyroid Presenting as a Giant Skull Lesion: A Dilemma in Treatment.

Gupta, R and Gupta, AK and Shankar, A and Bansal, S and Bhattacharya, A and Bal, A (2013) Insular Carcinoma of Thyroid Presenting as a Giant Skull Lesion: A Dilemma in Treatment. [Journal (On-line/Unpaginated)]

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Thyroid surgeons are becoming increasingly more aware of a histologically distinct subset of thyroid carcinoma whose classification falls between well-differentiated and anaplastic carcinomas with respect to both cell differentiation and clinical behavior. This subtype of tumors has been categorized as poorly differentiated or insular carcinoma, based on its characteristic cell groupings. Although the differentiation of insular carcinoma from other thyroid carcinomas has important prognostic and therapeutic significance, relatively little about insular carcinoma has been published in the otolaryngology literature. In this article, we discuss a case of insular carcinoma of thyroid presenting with concurrent distant metastasis to skull, lung, ribs, and inguinal region with review of the literature. We conclude that insular thyroid carcinoma warrants aggressive management with total thyroidectomy and excision of accessible giant lesion followed by radioactive iodine ablation of any remaining thyroid tissue.

Item Type:Journal (On-line/Unpaginated)
Keywords:Insular carcinoma; Thyroid; Metastasis; Treatment.
Subjects:JOURNALS > Online Journal of Health and Allied Sciences
ID Code:8939
Deposited By: Kakkilaya Bevinje, Dr. Srinivas
Deposited On:04 May 2013 23:09
Last Modified:04 May 2013 23:09

References in Article

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