?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Quantitative+morphology+of+human+hippocampus+early+neuron+development&rft.creator=Zaidel%2C+Dahlia+W.&rft.subject=Developmental+Psychology&rft.subject=Neuroanatomy&rft.subject=Neuroanatomy&rft.subject=Neurology&rft.subject=Neurophysiology&rft.description=Background%3A+Previous+findings+in+adults+revealed+significant+hemispheric+asymmetry+in+size+of+neuronal+somata+in+hippocampal+subfield+CA2+(the+%C2%93resistant+sector%C2%94)+with+no+age-related+changes.+Paucity+of+quantitative+data+on+the+developmental+status+of+these+%C2%93protected%C2%94+neurons+has+led+to+the+investigation+of+their+morphology+in+comparison+to+neurons+in+adjacent+subfield+CA3%2C+bilaterally.+Methods%3A+Bilateral+coronal+sections+from+postmortem+hippocampus%2C+24+and+76+weeks+postmenstrual+age+(gestational+age+plus+postnatal+age)+were+studied.+The+neurons+were+digitized+and+measured+on+a+computer.+Results%3A+Soma+size+correlated+positively+and+significantly+with+age+in+CA2+and+CA3%2C+bilaterally.+CA2+somata+were+significantly+larger+(left+34%25%2C+right+32%25)+than+adjacent+CA3+somata.+Variability+in+soma+form+or+size+increased+appreciably+with+age%2C+in+both+subfields%2C+bilaterally%2C+while+variability+in+soma+orientation+was+weakly+correlated+with+brain+growth.+Conclusions%3A+The+results+suggest+that+in+early+development+there+are+similarities+in+hemispheric+growth+patterns+in+CA2+and+CA3.+Large+CA2+soma+size+implies+axonal+connectivity+to+distantly+located+targets+very+early+in+development.+The+results+have+functional+implications%2C+including+memory%2C+to+brain+development&rft.date=1999-01&rft.type=Journal+(Paginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F152%2F3%2Fhippocampus.pdf&rft.identifier=++Zaidel%2C+Dahlia+W.++(1999)+Quantitative+morphology+of+human+hippocampus+early+neuron+development.++%5BJournal+(Paginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F152%2F