?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Approach+to+a+model+of+the+aging+phenomenon&rft.creator=Vanbremeersch%2C+Jean-Paul&rft.creator=Ehresmann%2C+Andr%C3%A9e+C.&rft.subject=Behavioral+Biology&rft.subject=Population+Biology&rft.subject=Complexity+Theory&rft.description=Numerous+physiological+theories+of+aging+have+been+proposed%3B+most+of+them+approach+the+problem+in+an+essentially+local+manner%2C+stressing+the+role+of+a+particular+factor+intervening+at+a+certain+level+and+the+resulting+pathological+consequences.+But+they+do+not+allow+for+a+combination+of+the+different+phenomena+observed+in+the+aging+process.+%0AThis+paper+proposes+a+more+unified+and+global+approach+to+this+process.+It+is+presented+in+the+frame+of+a+mathematical+model+for+complex+systems+with+a+hierarchy+of+internal+regulation+centers+(CR)%2C+developed+by+the+authors+in+preceding+papers%3B+the+dynamics+of+such+a+system+depends+on+a+dialectics+between+these+CRs+due+to+their+different+complexity+level+and+different+timescales.+%0AAging+for+an+organism+is+described+as+a+consequence+of+this+dialectics%2C+that+progressively+triggers+a+%22cascade+of+de%2Fresynchronizations%22+between+the+CRs%2C+resulting+from+the+reduction+in+stability+of+complex+components+(increase+in+turnover+or+acceleration+of+degradation)+and+the+increase+in+transmission+delays+for+functioning+and+repair.+This+temporal+imbalance+comes+from+the+interplay+between+external+stochastic+disturbances+and+more+or+less+predetermined+sub-systems+with+limited+capacities+for+repair.%0A&rft.date=1992-11&rft.type=Departmental+Technical+Report&rft.type=PeerReviewed&rft.format=text%2Fhtml&rft.identifier=http%3A%2F%2Fcogprints.org%2F1654%2F1%2FEVAgeing.htm&rft.identifier=++Vanbremeersch%2C+Jean-Paul+and+Ehresmann%2C+Andr%C3%A9e+C.++(1992)+Approach+to+a+model+of+the+aging+phenomenon.++%5BDepartmental+Technical+Report%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F1654%2F