?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Vaccine+strategy+when+the+smallpox+model+fails%3A+1.+immune+cognition%2C+Malaria+and+the+Fulani&rft.creator=Wallace%2C+Rodrick&rft.creator=Wallace%2C+Robert+G&rft.subject=Theoretical+Biology&rft.description=We+begin+to+examine+the+implications+of+IR+Cohen's+work+on+immune+cognition+%5B1-3%5D+for+vaccine+strategies+when+simple+%0Aelicitation+of+sterilizing+immunity+fails%2C+as+is+the+case%0Afor+HIV%2C+tuberculosis%2C+and+malaria.++Cohen's+approach+takes+on+a+special+importance+in+the+context+of+recent+work+by+Nisbett+et+al.+%5B4%5D+showing+clearly+that+central+nervous+system+(CNS)+cognition+is+not+universal%2C+but+rather+differs+fundamentally+for+populations+having+different+cultural+systems.++A+growing+body+of+evolutionary+anthropology+indeed+suggests+that+such+effects+are+inevitable%2C+since+culture+is+as+much+a+part+of+human+biology+'as+the+enamel+on+our+teeth.'++Thus+a+successful+vaccine+strategy+for+use+when+the++smallpox+model+fails+must+address+a+condensation+of+sociocultural+and+immune+cognition%2C+in+the+same+sense+that+neuroimmunology+and+immunogenetics+describe+the+condensation+of+CNS+and+genetic+'languages'+with+immune+function.++We+reinterpret+recent+studies+of+African+cultural+variation+in+immune+response+to+malaria+from+this+perspective.&rft.date=2001-07&rft.type=Preprint&rft.type=NonPeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F1665%2F3%2Fvaccine1.pdf&rft.identifier=++Wallace%2C+Rodrick+and+Wallace%2C+Robert+G++(2001)+Vaccine+strategy+when+the+smallpox+model+fails%3A+1.+immune+cognition%2C+Malaria+and+the+Fulani.++%5BPreprint%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F1665%2F