TY  - GEN
ID  - cogprints1665
UR  - http://cogprints.org/1665/
A1  - Wallace, Rodrick
A1  - Wallace, Robert G
TI  - Vaccine strategy when the smallpox model fails: 1. immune cognition, Malaria and the Fulani
Y1  - 2001/07//
N2  - We begin to examine the implications of IR Cohen's work on immune cognition [1-3] for vaccine strategies when simple 
elicitation of sterilizing immunity fails, as is the case
for HIV, tuberculosis, and malaria.  Cohen's approach takes on a special importance in the context of recent work by Nisbett et al. [4] showing clearly that central nervous system (CNS) cognition is not universal, but rather differs fundamentally for populations having different cultural systems.  A growing body of evolutionary anthropology indeed suggests that such effects are inevitable, since culture is as much a part of human biology 'as the enamel on our teeth.'  Thus a successful vaccine strategy for use when the  smallpox model fails must address a condensation of sociocultural and immune cognition, in the same sense that neuroimmunology and immunogenetics describe the condensation of CNS and genetic 'languages' with immune function.  We reinterpret recent studies of African cultural variation in immune response to malaria from this perspective.
AV  - public
KW  - Africa
KW  -  AIDS
KW  -  Fulani
KW  -  immune cognition
KW  -  information theory
KW  -  malaria
KW  -  tuberculosis
KW  -  vaccine strategy
ER  -

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