--- abstract: |- We begin to examine the implications of IR Cohen's work on immune cognition [1-3] for vaccine strategies when simple elicitation of sterilizing immunity fails, as is the case for HIV, tuberculosis, and malaria. Cohen's approach takes on a special importance in the context of recent work by Nisbett et al. [4] showing clearly that central nervous system (CNS) cognition is not universal, but rather differs fundamentally for populations having different cultural systems. A growing body of evolutionary anthropology indeed suggests that such effects are inevitable, since culture is as much a part of human biology 'as the enamel on our teeth.' Thus a successful vaccine strategy for use when the smallpox model fails must address a condensation of sociocultural and immune cognition, in the same sense that neuroimmunology and immunogenetics describe the condensation of CNS and genetic 'languages' with immune function. We reinterpret recent studies of African cultural variation in immune response to malaria from this perspective. altloc: [] chapter: ~ commentary: ~ commref: ~ confdates: ~ conference: ~ confloc: ~ contact_email: ~ creators_id: [] creators_name: - family: Wallace given: Rodrick honourific: '' lineage: '' - family: Wallace given: Robert G honourific: '' lineage: '' date: 2001-07 date_type: published datestamp: 2001-07-02 department: ~ dir: disk0/00/00/16/65 edit_lock_since: ~ edit_lock_until: ~ edit_lock_user: ~ editors_id: [] editors_name: [] eprint_status: archive eprintid: 1665 fileinfo: /style/images/fileicons/application_pdf.png;/1665/3/vaccine1.pdf full_text_status: public importid: ~ institution: ~ isbn: ~ ispublished: ~ issn: ~ item_issues_comment: [] item_issues_count: 0 item_issues_description: [] item_issues_id: [] item_issues_reported_by: [] item_issues_resolved_by: [] item_issues_status: [] item_issues_timestamp: [] item_issues_type: [] keywords: 'Africa, AIDS, Fulani, immune cognition, information theory, malaria, tuberculosis, vaccine strategy' lastmod: 2011-03-11 08:54:44 latitude: ~ longitude: ~ metadata_visibility: show note: ~ number: ~ pagerange: ~ pubdom: FALSE publication: ~ publisher: ~ refereed: FALSE referencetext: ~ relation_type: [] relation_uri: [] reportno: ~ rev_number: 12 series: ~ source: ~ status_changed: 2007-09-12 16:39:30 subjects: - bio-theory succeeds: 1543 suggestions: ~ sword_depositor: ~ sword_slug: ~ thesistype: ~ title: 'Vaccine strategy when the smallpox model fails: 1. immune cognition, Malaria and the Fulani' type: preprint userid: 1845 volume: ~