TY  - GEN
ID  - cogprints1731
UR  - http://cogprints.org/1731/
A1  - Wallace, Rodrick
A1  - Fullilove, Mindy
A1  - Wallace, Deborah
TI  - Immune cognition, social justice and asthma: structured stress and the developing immune system
Y1  - 2001/08//
N2  - We explore the implications of IR Cohen's work on immune
cognition for understanding rising rates of asthma morbidity
and mortality in the US.  Immune cognition is conjoined with
central nervous system cognition, and with the cognitive
function of the embedding sociocultural networks by which
individuals are acculturated and through which they work with others to meet challenges of threat and opportunity.
Using a mathematical model, we find that externally-
imposed patterns of 'structured stress' can, through their
effect on a child's socioculture, become synergistic with
the development of immune cognition, triggering the persistence of an atopic Th2 phenotype, a necessary precursor to asthma and other immune disease.  Reversal of the rising tide of asthma and related chronic diseases in the US thus seems unlikely without a 21st Century version of the earlier Great Urban Reforms which ended the scourge of infectious diseases.
AV  - public
KW  - American Apartheid
KW  -  asthma
KW  -  atopy
KW  -  immune cognition
KW  -  information theory
KW  -  large deviation theory
KW  -  renormalization
KW  -  stress
ER  -

<script src='https://archive-bar.soton.ac.uk/archive-bar.js'></script>
<script src='https://archive-bar.soton.ac.uk/google-analytics.js'></script>