?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Cerebral+cortex+neurons+with+extra+spikes%3A+a+normal+substrate+for+epileptic+discharges%3F&rft.creator=Calvin%2C+William+H.&rft.creator=Sypert%2C+George+W.&rft.subject=Neurology&rft.description=Double+spikes+during+otherwise+rhythmic+discharge+were+frequently+observed+in+'fast'+pyramidal+tract+neurons+in+response+to+steady+depolarizing+currents+injected+through+the+recording+micropipette.+The+extra+spike+appears+to+arise+from+a+large+depolarizing+afterpotential+crossing+the+falling+threshold+several+milliseconds+following+a+spike%3B+extra+spikes+themselves+may+generate+further+extra+spikes+in+a+similar+manner%2C+generating+burst+patterns+which+are+strikingly+similar+to+those+of+epileptic+neurons.&rft.date=1975&rft.type=Journal+(Paginated)&rft.type=PeerReviewed&rft.format=text%2Fhtml&rft.identifier=http%3A%2F%2Fcogprints.org%2F19%2F1%2F1975BrainRes.htm&rft.identifier=++Calvin%2C+William+H.+and+Sypert%2C+George+W.++(1975)+Cerebral+cortex+neurons+with+extra+spikes%3A+a+normal+substrate+for+epileptic+discharges%3F++%5BJournal+(Paginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F19%2F