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<> "The repository administrator has not yet configured an RDF license."^^ . <> . . "Dehydroepiandrosterone sulphate and corticotropin levels are high in young male patients with conduct disorder: comparisons with growth factors, thyroid and gonadal hormones"^^ . "Introduction: The biological concomitants of childhood conduct disorder (CD) have seldom been considered separate from those of hyperkinesis with which CD is often comorbid. CD predicts an increased likelihood of developing a personality disorder and is often associated with an antisocial outcome. Childhood CD may originate in a stressful upbringing in a dysfunctional family environment, and has been reported to be associated with unusual physical or sexual development and thyroid dysfunction. \n\nMethods: We therefore explored circulating levels of hormones from adrenal, gonadal and growth-hormone axes associated with stress, aggression and development in 28 CD patients and 13 age-matched healthy children (10-18 years old). \n\nResults: \n1/ The CD group had higher levels of dehydroepiandrosterone sulphate (DHEA-S) and corticotropin (ACTH) and for those under 14 years of age there was more free triiodothyronine (fT3) in the circulation. \n2/ There were no differences for gonadal hormones, and neither the levels of steroid hormones nor the ratings of maturity (early/late) were associated with aggression, as has been reported elsewhere. 3/ Smaller physical measures in CD children correlated with DHEA-S and growth factors (e.g. IGF-I): 4/ increased ACTH and fT3 correlated with restless-impulsive ratings, and DHEA-S with 'disruptive behaviour'. \n\nConclusions: Imbalances in the adrenal and growth axes may indeed have neurotrophic repercussions in growth and development.\n\n"^^ . "2001" . . "43" . . "Karger"^^ . . . "Neuropsychobiology"^^ . . . . . . . . . . . . . . . . . ""^^ . "Dmitrieva"^^ . " Dmitrieva"^^ . . ""^^ . "Oades"^^ . " Oades"^^ . . ""^^ . "Hauffa"^^ . " Hauffa"^^ . . ""^^ . "Eggers"^^ . " Eggers"^^ . . . . . . "Dehydroepiandrosterone sulphate and corticotropin levels are high in young male patients with conduct disorder: comparisons with growth factors, thyroid and gonadal hormones (PDF)"^^ . . . . . . "CD-Neuropsychobiol-2001-art.pdf"^^ . . "HTML Summary of #2018 \n\nDehydroepiandrosterone sulphate and corticotropin levels are high in young male patients with conduct disorder: comparisons with growth factors, thyroid and gonadal hormones\n\n" . "text/html" . . . "Developmental Psychology" . . . "Neuroendocrinology" . . . "Neuropsychiatry" . . . "Psychobiology" . .