creators_name: Wallace, Rodrick creators_name: Wallace, Deborah creators_name: Wallace, Robert creators_id: New York State Psychiatric Institute creators_id: Mailman School of Public Health, Columbia University creators_id: City University of New York type: preprint datestamp: 2002-08-15 lastmod: 2011-03-11 08:54:59 metadata_visibility: show title: Culture and Cancer subjects: bio-theory full_text_status: public keywords: Cancer, cellular cognition, culture, evolution, information theory, interpenetration, mutator, punctuation, renormalization, second order selection, universality abstract: Genetic mechanisms, since they broadly involve information transmission, should be translatable into information dynamics formalism. From this perspective we reconsider the adaptive mutator, one possible means of 'second order selection' by which a highly structured 'language' of environment and development writes itself onto the variation upon which evolutionary selection and tumorigenesis operate. Our approach uses recent results in the spirit of the Large Deviations Program of applied probability that permit transfer of phase transition approaches from statistical mechanics to information theory, generating evolutionary and developmental punctuation in what we claim to be a highly natural manner. date: 2002-08 date_type: published refereed: FALSE citation: Wallace, Dr. Rodrick and Wallace, Dr. Deborah and Wallace, Dr. Robert (2002) Culture and Cancer. [Preprint] document_url: http://cogprints.org/2407/1/mutator2.pdf