?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Subthreshold+dynamics+of+the+neural+membrane+potential+driven+by+stochastic+synaptic+input&rft.creator=Hillenbrand%2C+Dr.+Ulrich&rft.subject=Biophysics&rft.subject=Computational+Neuroscience&rft.subject=Theoretical+Biology&rft.description=In+the+cerebral+cortex%2C+neurons+are+subject+to+a+continuous+bombardment+of+synaptic+inputs+originating+from+the+network's+background+activity.+This+leads+to+ongoing%2C+mostly+subthreshold+membrane+dynamics+that+depends+on+the+statistics+of+the+background+activity+and+of+the+synapses+made+on+a+neuron.+Subthreshold+membrane+polarization+is%2C+in+turn%2C+a+potent+modulator+of+neural+responses.+The+present+paper+analyzes+the+subthreshold+dynamics+of+the+neural+membrane+potential+driven+by+synaptic+inputs+of+stationary+statistics.+Synaptic+inputs+are+considered+in+linear+interaction.+The+analysis+identifies+regimes+of+input+statistics+which+give+rise+to+stationary%2C+fluctuating%2C+oscillatory%2C+and+unstable+dynamics.+In+particular%2C+I+show+that+(i)+mere+noise+inputs+can+drive+the+membrane+potential+into+sustained%2C+quasiperiodic+oscillations+(noise-driven+oscillations)%2C+in+the+absence+of+a+stimulus-derived%2C+intraneural%2C+or+network+pacemaker%3B+(ii)+adding+hyperpolarizing+to+depolarizing+synaptic+input+can+increase+neural+activity+(hyperpolarization-induced+activity)%2C+in+the+absence+of+hyperpolarization-activated+currents.&rft.date=2002&rft.type=Journal+(On-line%2FUnpaginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F2480%2F1%2FHillenbrand_02.pdf&rft.identifier=++Hillenbrand%2C+Dr.+Ulrich++(2002)+Subthreshold+dynamics+of+the+neural+membrane+potential+driven+by+stochastic+synaptic+input.++%5BJournal+(On-line%2FUnpaginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F2480%2F