%A Dr. Ulrich Hillenbrand %A Prof. Dr. J. Leo van Hemmen %J Philosophical Transactions of the Royal Society: Biological Sciences %T Adaptation in the Corticothalamic Loop: Computational Prospects of Tuning the Senses %X The present article discusses computational hypotheses on corticothalamic feedback and modulation of cortical response properties. We have recently proposed the two phenomena to be related, hypothesizing that neuronal velocity preference in the visual cortex is altered by feedback to the lateral geniculate nucleus. We now contrast the common view that response adaptation to stimuli subserves a function of redundancy reduction with the idea that it may enhance cortical representation of objects. Our arguments lead to the concept that the corticothalamic loop is involved in reducing sensory input to behaviorally relevant aspects, a pre-attentive gating. %K Corticothalamic Loop, Feedback, Adaptation, Velocity Tuning, Object Segmentation, Pre-attentive Gating %P 1859-1867 %V 357 %D 2002 %L cogprints2721