?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=The+causal+consciousness%3A+beta-neurexin+promotes+neuromediator+release+via+vibrational+multidimensional+tunneling&rft.creator=Georgiev%2C+Dr.+Danko&rft.subject=Biophysics&rft.subject=Neurophysiology&rft.subject=Neurochemistry&rft.description=Epiphenomenalism+is+shown+to+be+absurd+because+the+development+of+consciousness+must+be+explainable+through+natural+selection.+A+detailed+neuromolecular+basis+of+the+neuromediator+release+is+given+and+it+is+stressed+on+the+possible+key+point+where+the+quantum+mind+could+act%2C+namely+presynaptic+scaffold+protein+dynamics+and+detachment+of+the+calcium+sensor+v-SNARE+synaptotagmin-1.+The+beta-neurexin+molecules+are+tuned+via+fast+propagating+solitons+by+the+quantum+coherent+microtubule+network+so+that+the+beta-neurexin+molecule+thermal+vibrations+could+promote+or+suppress+conformational+changes+via+vibrational+multidimensional+tunneling%2C+which+drives+synaptotagmin-1+detachment+from+the+SNARE+complex+under+calcium+ion+binding.+Following+the+synaptotagmin-1+detachment+membrane+fusion+takes+place+in+SNARE+dependent+fashion+and+the+presynaptic+vesicle+spills+neuromediator+in+the+synaptic+cleft.+Thus+the+quantum+transfer+of+information+causally+affects+the+neuromediator+release.&rft.date=2003-03&rft.type=Preprint&rft.type=NonPeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F2809%2F1%2Fcausal.pdf&rft.identifier=++Georgiev%2C+Dr.+Danko++(2003)+The+causal+consciousness%3A+beta-neurexin+promotes+neuromediator+release+via+vibrational+multidimensional+tunneling.++%5BPreprint%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F2809%2F