?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Structured+Psychosocial+Stress+and+Therapeutic+Intervention%3A+Toward+a+Realistic+Biological+Medicine&rft.creator=Wallace%2C+Rodrick&rft.subject=Applied+Cognitive+Psychology&rft.description=Using+generalized+'language+of+thought'+arguments+appropriate+to+interacting+cognitive+modules%2C+we+explore+how+disease+states+can+interact+with+medical+treatment%2C+including%2C+but+not+limited+to%2C+drug+therapy.++The+feedback+between+treatment+and+response+creates+a+kind+of+idiotypic+'hall+of+mirrors'+generating+a+pattern+of+'efficacy'%2C+'treatment+failure'%2C+and+'adverse+reactions'+which+will%2C+from+a+Rate+Distortion+perspective%2C+embody+a+distorted+image+of+externally-imposed+structured+psychosocial+stress.++This+analysis%2C+unlike+current+pharmacogenetics%2C+does+not+either+reify+'race'+or+blame+the+victim+by+using+genetic+structure+to+place+the+locus-of-control+within+a+group+or+individual.++Rather%2C+it+suggests+that+a+comparatively+simple+series+of+questions+to+identify+longitudinal+and+cross-sectional+stressors+may+provide+more+effective+guidance+for+specification+of+individual+therapy+than+complicated+genotyping+strategies+of+dubious+meaning.++These+latter+are+likely+to+be+both+very+expensive+and+utterly+blind+to+the+impact+of+structured+psychosocial+stress+--+a+euphemism+for+various+forms+of+racism+and+ethnic+cleansing+--+which%2C+we+contend%2C+is+often+a+principal+determinant+of+treatment+outcome+at+both+individual+and+community+levels+of+organization.++We+propose%2C+to+effectively+address+'health+disparities'+between+populations%2C+and+in+contrast+to+current+biomedical+ideology+based+on+a+simplistic+genetic+determinism%2C+a+richer+program+of+biological+medicine+reflecting+Lewontin's+'triple+helix'+of+genes%2C+environment%2C+and+development%2C+a+program+more+in+concert+with+the+realities+of+a+basic+human+biology+marked+by+hypersociality+unusual+in+vertibrates.++Aggressive+social%2C+economic%2C+and+other+policies+of+affirmative+action+to+redress+the+persisting+burdens+of+history+would+be+an+integral+component+of+any+such+project.&rft.date=2003&rft.type=Preprint&rft.type=NonPeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F3002%2F1%2Fdrug2.pdf&rft.identifier=++Wallace%2C+Rodrick++(2003)+Structured+Psychosocial+Stress+and+Therapeutic+Intervention%3A+Toward+a+Realistic+Biological+Medicine.++%5BPreprint%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F3002%2F