@misc{cogprints33,
          volume = {23},
           title = {Bi- and Multivariate Analyses of Diallel Crosses: A Tool for the Genetic Dissection of Neurobehavioral Phenotypes},
          author = {Wim E. Crusio},
            year = {1993},
           pages = {59--67},
         journal = {Behavior Genetics},
        keywords = {diallel cross, genetic correlations, multivariate analysis, brain-behavior relationships, neurobehavioral genetics, exploratory activity, mouse},
             url = {http://cogprints.org/33/},
        abstract = {The genetic-correlational approach provides a very powerful tool for the analysis of causal relationships between phenotypes. It appears to be particularly appropriate for investigating the functional organization of behavior and/or of causal relationships between brain and behavior. A method for the bivariate analysis of diallel crosses that permits the estimation of correlations due to environmental effects, additive-genetic effects, and/or dominance deviations is described, together with a worked-out example stemming from a five times replicated 4 x 4 diallel cross between inbred mouse strains. The phenotypes chosen to illustrate the analysis were locomotor activity and rearing frequency in an open field. Large, positive additive-genetic and dominance correlations between these two phenotypes were obtained. This finding was replicated in another, independently-executed, diallel cross.}
}

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