TY  - GEN
ID  - cogprints3316
UR  - http://cogprints.org/3316/
A1  -  KATZ, EMILY
A1  - ROTHSCHILD, OLIVER
A1  - HERRERA, ANDRIANA
A1  -  HUANG, SOFIA
A1  - WONG, ANNA
A1  - WOJCIECHOWSKI, YVETTE
A1  - GIL, AIDA
A1  - YAN, QI JIANG
A1  - BAUCHWITZ, ROBERT
TI  - Odor Based Behavioral Tasks Confounded by Distance Dependent Detection: Modification of a Murine Digging Paradigm
Y1  - 2003/12//
N2  - Tests of murine higher order cognition are important in order to fully explore the effects of genetic alterations and potential therapies in models of human mental retardation and other deficits of intellect. In this study, inbred and F1 hybrid strains of mice were assessed in a five odor sequence task previously described for rats which employs buried food rewards. Data are provided indicating that the use of buried rewards in mouse olfactory digging tasks should be approached with significant caution. An alternate test of sequence dependent working memory (2-sequence task) using a post choice, drop-in food reward is described. After achievement of stable average plateau scores, a streak and slump pattern, rather than near errorless performance, was observed. Therefore, mice do not appear to effortlessly acquire sequences of odors in a working memory paradigm in which rewarded odors are constantly changing. 
AV  - public
KW  - sequence memory
KW  -  learning set
KW  -  olfactory discrimination
KW  -  digging tasks
KW  -  episodic memory
KW  -  Murine Olfactory Sequence Tasks
KW  -  mouse
KW  -  rat
KW  -  rodent
ER  -

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