creators_name: Baianu, I.C.
creators_id: icb
editors_name: Landahl, H.D.
type: journalp
datestamp: 2004-10-06
lastmod: 2011-03-11 08:55:41
metadata_visibility: show
title: STRUCTURAL ORDER AND PARTIAL DISORDER IN BIOLOGICAL SYSTEMS:
STRUCTURAL "FUZZINESS" UNDERLYING BIOLOGICAL FUNCTION
ispublished: pub
subjects: comp-sci-stat-model
subjects: comp-sci-mach-dynam-sys
subjects: comp-sci-complex-theory
subjects: comp-sci-neural-nets
subjects: bio-theory
full_text_status: public
keywords: structural order and partial disorder in biological systems;
paracrystaline nerve myelin computer models; paracrystalline DNA fibers and computer models of partailly disordered DNA fibers; relationship between structural "fuzziness" and biological function;electron density of states in biological structures;quantum theoretical computations for lattices in solids;Anderson delocalization, Hall effect and quantum tunneling effects on important biological functions;Novel experiments by pulsed lasers, pulsed/FT-NMR and optical/NIR spectroscopy;
monitoring the effects of structural partial disorder and "fuzziness" on biological function.
abstract: The presence of structural order and partial disorder is discussed for several important biological molecules such as DNA, enzymes and proteins, as well as for cellular structures such as nerve myelin. The relationship between structural "fuzziness" and biological function is discussed
as an important aspect of biological complexity and biodynamics. The possible effects of partial disorder on the electron density of states in biological structures is predicted based on known quantum theoretical computations for lattices in solids. Important phenomena such as Anderson delocalization, Hall effect and quantum tunneling are predicted to affect biological function. Novel experiments are being suggested by pulsed lasers, pulsed/FT-NMR and optical/NIR spectroscopy in order to monitor the effects of structural partial disorder and "fuzziness" on biological function. Novel methods for computer analysis of paracrystalline lattices such as nerve myelin and oriented DNA fibers are also being proposed based on molecular models that include partial disorder.
date: 1980-09
date_type: published
publication: The Bulletin of Mathematical Biophysics
volume: 42
number: 4
publisher: Pergamon Press Ltd.
pagerange: 137-141
refereed: TRUE
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citation: Baianu, Dr. I.C. (1980) STRUCTURAL ORDER AND PARTIAL DISORDER IN BIOLOGICAL SYSTEMS: STRUCTURAL "FUZZINESS" UNDERLYING BIOLOGICAL FUNCTION. [Journal (Paginated)]
document_url: http://cogprints.org/3820/1/Letter_html2.htm