?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Solitonic+effects+of+the+local+electromagnetic+field+on+neuronal+microtubules+%E2%80%93+tubulin+tail+sine-Gordon+solitons+could+control+MAP+attachment+sites+and+microtubule+motor+protein+function&rft.creator=Georgiev%2C+Danko&rft.subject=Biophysics&rft.subject=Neurophysiology&rft.description=The+current+wisdom+in+the+classical+neural+net+theory+holds+that+the+only+direct+action+of+the+electric+field+in+neurons+is+upon+voltage-gated+ion+channels%2C+which+open+and+close+their+gates+for+ions.+The+intraneuronal+biochemical+activities+are+thought+to+be+modulated+indirectly+either+by+the+entering+in+the+cytoplasm+ions+that+act+as+second+messengers+or+via+linked+to+the+ion+channels+enzymes.+In+this+paper+we+present+a+novel+possibility+for+subneuronal+processing+of+information+by+cytoskeletal+microtubule+tubulin+tails+and+we+show+that+the+local+electromagnetic+field+brings+information+that+could+be+converted+into+specific+protein+tubulin+tail+conformational+states.+Long-range+collective+coherent+behavior+of+the+tubulin+tails+could+transmit+solitary+waves+in+the+form+of+sine-Gordon+kinks%2C+antikinks+or+breathers+along+the+microtubule+outer+surface+and+the+tubulin+tail+soliton+collisions+could+serve+as+elementary+computational+gates+that+control+cytoskeletal+processes.+The+biological+importance+of+the+presented+model+is+due+to+the+unique+biological+enzymatic+energase+action+of+the+tubulin+tails%2C+which+is+experimentally+shown+to+control+the+sites+of+microtubule-associated+protein+attachment+and+the+kinesin+transport+of+post-Golgi+vesicles.&rft.date=2004-10&rft.type=Preprint&rft.type=NonPeerReviewed&rft.format=text%2Fhtml&rft.identifier=http%3A%2F%2Fcogprints.org%2F3894%2F1%2FTubulin_tail_solitons.htm&rft.identifier=++Georgiev%2C+Danko++(2004)+Solitonic+effects+of+the+local+electromagnetic+field+on+neuronal+microtubules+%E2%80%93+tubulin+tail+sine-Gordon+solitons+could+control+MAP+attachment+sites+and+microtubule+motor+protein+function.++%5BPreprint%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F3894%2F