?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Risk+Factors+for+Invasive+Epithelial+Ovarian+Cancer+by+Histologic+Subtype&rft.creator=Thomas+Quirk%2C+Jeffrey&rft.creator=Nachimuthu%2C+Natarajan&rft.creator=James+Mettlin%2C+Curtis&rft.creator=Barbara+Moysich%2C+Kirsten&rft.creator=Swede%2C+Helen&rft.subject=Online+Journal+of+Health+and+Allied+Sciences&rft.description=It+is+unclear+whether+the+different+histologic+subtypes+of+epithelial+ovarian+carcinoma+have+different+risk+factors.+We+investigated+the+relationships+between+selected+epidemiologic+variables+(i.e.%2C+parity%2C+family+history+of+ovarian+cancer%2C+oral+contraceptive+use%2C+a+history+of+tubal+ligation+and+noncontraceptive+estrogen+use)+and+the+major+histologic+subtypes+of+epithelial+ovarian+cancer+in+a+hospital-based+case-control+study+of+adult+women+at+Roswell+Park+Cancer+Institute+in+Buffalo%2C+NY%2C+USA.+Multivariate+unconditional+logistic+regression+models+were+used+for+statistical+analysis.+We+observed+a+pattern+of+increased+risk+associated+with+family+history+and+a+pattern+of+risk+reduction+associated+with+parity%2C+noncontraceptive+estrogen+use+and+tubal+ligation+across+all+histologic+subtype+groups.+However%2C+we+did+not+observe+a+consistent+pattern+of+risk+associated+with+oral+contraceptive+use.+These+results+provide+some+additional+support+for+the+hypothesis+that+the+effects+of+various+ovarian+cancer+risk+factors+may+differ+according+to+the+histologic+subtype.&rft.publisher=Dr.+B.S.+Kakkilaya&rft.contributor=Kakkilaya+Bevinje%2C+Dr.+Srinivas&rft.date=2004-10&rft.type=Journal+(On-line%2FUnpaginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F3898%2F1%2F2004-3-2.pdf&rft.identifier=++Thomas+Quirk%2C+Jeffrey+and+Nachimuthu%2C+Natarajan+and+James+Mettlin%2C+Curtis+and+Barbara+Moysich%2C+Kirsten+and+Swede%2C+Helen++(2004)+Risk+Factors+for+Invasive+Epithelial+Ovarian+Cancer+by+Histologic+Subtype.++%5BJournal+(On-line%2FUnpaginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F3898%2F