TY  - GEN
ID  - cogprints3961
UR  - http://cogprints.org/3961/
A1  - Gorban, Alexander N.
A1  - Zinovyev, Andrey Yu.
A1  - Wunsch, Donald C.
TI  - Application of The Method of Elastic Maps In Analysis of Genetic Texts
Y1  - 2003///
N2  - Abstract - Method of elastic maps ( http://cogprints.ecs.soton.ac.uk/archive/00003088/ and
http://cogprints.ecs.soton.ac.uk/archive/00003919/ )
allows us to construct efficiently 1D, 2D and 3D non-linear approximations to the principal manifolds with different topology (piece of plane, sphere, torus etc.) and to project data onto it. We describe the idea of the method and demonstrate its applications in analysis of genetic sequences. The animated 3D-scatters are available on our web-site: http://www.ihes.fr/~zinovyev/7clusters/ 
We found the universal cluster structure of genetic sequences, and demonstrated the thin structure of these clusters for coding regions. This thin structure is related to different translational efficiency.
AV  - public
KW  - SOM
KW  -  Elastic net
KW  -  Data modeling
KW  -  Genome clusters
KW  -  Genetic text
KW  -  Translational efficiency
ER  -

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