title: New Concepts in Pacemaker Syndrome 
creator: Farmer, Michael D
creator: Estes, Mark NA III
creator: Link, Mark S
subject: Indian Pacing and Electrophysiology Journal
description: After implantation of a permanent pacemaker, patients may experience severe symptoms of dyspnea, palpitations, malaise, and syncope resulting from pacemaker syndrome.  Although pacemaker syndrome is most often ascribed to the loss of atrioventricular (A-V) synchrony, more recent data may also implicate left ventricular dysynchrony caused by right ventricular pacing.  Previous studies have not shown reductions in mortality or stroke with rate-modulated dual-chamber (DDDR) pacing as compared to ventricular-based (VVI) pacing. The benefits in A-V sequential pacing with the DDDR mode are likely mitigated by the interventricular (V-V) dysynchrony imposed by the high percentage of ventricular pacing commonly seen in the DDDR mode.  Programming DDDR pacemakers to encourage intrinsic A-V conduction and reduce right ventricular pacing will likely decrease heart failure and pacemaker syndrome.  Studies are currently ongoing to address these questions. 
publisher: Indian Pacing and Electrophysiology Group
contributor: Singh, Balbir
contributor: Lokhandwala, Yash
contributor: Francis, Johnson
contributor: Gupta, Anup
date: 2004-10
type: Journal (Paginated)
type: PeerReviewed
format: application/pdf
identifier: http://cogprints.org/4184/1/link.pdf
format: text/html
identifier: http://cogprints.org/4184/2/link.htm
identifier:   Farmer, Michael D and Estes, Mark NA III and Link, Mark S  (2004) New Concepts in Pacemaker Syndrome.  [Journal (Paginated)]     
relation: http://cogprints.org/4184/