TY  - GEN
ID  - cogprints4184
UR  - http://cogprints.org/4184/
A1  - Farmer, Michael D
A1  - Estes, Mark NA III
A1  - Link, Mark S
Y1  - 2004/10//
N2  - After implantation of a permanent pacemaker, patients may experience severe symptoms of dyspnea, palpitations, malaise, and syncope resulting from pacemaker syndrome.  Although pacemaker syndrome is most often ascribed to the loss of atrioventricular (A-V) synchrony, more recent data may also implicate left ventricular dysynchrony caused by right ventricular pacing.  Previous studies have not shown reductions in mortality or stroke with rate-modulated dual-chamber (DDDR) pacing as compared to ventricular-based (VVI) pacing. The benefits in A-V sequential pacing with the DDDR mode are likely mitigated by the interventricular (V-V) dysynchrony imposed by the high percentage of ventricular pacing commonly seen in the DDDR mode.  Programming DDDR pacemakers to encourage intrinsic A-V conduction and reduce right ventricular pacing will likely decrease heart failure and pacemaker syndrome.  Studies are currently ongoing to address these questions.

PB  - Indian Pacing and Electrophysiology Group
KW  - VVI = ventricular-based
KW  -  VVIR = rate modulated ventricular-based
KW  -  A-V = atrioventricular
KW  -  V-V = interventricular
KW  -  V-A = ventricular-atrial
KW  -  LBBB = left bundle branch block
KW  -  LVEF = left ventricular ejection fraction
KW  -  DDDR = rate modulated dual-chamber
KW  -  SND = sinus node dysfunction
KW  -  AAI = single-chamber atrial
KW  -  AF = atrial fibrillation
KW  -  LV = left ventricular
KW  -  RV= right ventricular

TI  - New Concepts in Pacemaker Syndrome

SP  - 195
AV  - public
EP  - 200
ER  -

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