?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Ventricular+Tachycardia+in+the+Absence+of+Structural+Heart+Disease&rft.creator=Srivathsan%2C+Komandoor&rft.creator=Lester%2C+Steven+J&rft.creator=Appleton%2C+Christopher+P&rft.creator=Scott%2C+Luis+R+P&rft.creator=Munger%2C+Thomas+M&rft.subject=Indian+Pacing+and+Electrophysiology+Journal&rft.description=++++++++++++In+up+to+10%25+of+patients+who+present+with+ventricular+tachycardia+(VT)%2C+obvious+structural+heart+disease+is+not+identified.+In+such+patients%2C+causes+of+ventricular+arrhythmia+include+right+ventricular+outflow+tract+(RVOT)+VT%2C+extrasystoles%2C+idiopathic+left+ventricular+tachycardia+(ILVT)%2C+idiopathic+propranolol-sensitive+VT+(IPVT)%2C+catecholaminergic+polymorphic+VT+(CPVT)%2C+Brugada+syndrome%2C+and+long+QT+syndrome+(LQTS).+RVOT+VT%2C+ILVT%2C+and+IPVT+are+referred+to+as+idiopathic+VT+and+generally+do+not+have+a+familial+basis.+RVOT+VT+and+ILVT+are+monomorphic%2C+whereas+IPVT+may+be+monomorphic+or+polymorphic.+The+idiopathic+VTs+are+classified+by+the+ventricle+of+origin%2C+the+response+to+pharmacologic+agents%2C+catecholamine+dependence%2C+and+the+specific+morphologic+features+of+the+arrhythmia.+CPVT%2C+Brugada+syndrome%2C+and+LQTS+are+inherited+ion+channelopathies.+CPVT+may+present+as+bidirectional+VT%2C+polymorphic+VT%2C+or+catecholaminergic+ventricular+fibrillation.+Syncope+and+sudden+death+in+Brugada+syndrome+are+usually+due+to+polymorphic+VT.+The+characteristic+arrhythmia+of+LQTS+is+torsades+de+pointes.+Overall%2C+patients+with+idiopathic+VT+have+a+better+prognosis+than+do+patients+with+ventricular+arrhythmias+and+structural+heart+disease.+Initial+treatment+approach+is+pharmacologic+and+radiofrequency+ablation+is+curative+in+most+patients.+However%2C+radiofrequency+ablation+is+not+useful+in+the+management+of+inherited+ion+channelopathies.+Prognosis+for+patients+with+VT+secondary+to+ion+channelopathies+is+variable.+High-risk+patients+(recurrent+syncope+and+sudden+cardiac+death+survivors)+with+inherited+ion+channelopathies+benefit+from+implantable+cardioverter-defibrillator+placement.+This+paper+reviews+the+mechanism%2C+clinical+presentation%2C+and+management+of+VT+in+the+absence+of+structural+heart+disease.%0A&rft.publisher=Indian+Pacing+and+Electrophysiology+Group&rft.contributor=Singh%2C+Balbir&rft.contributor=Lokhandwala%2C+Yash&rft.contributor=Francis%2C+Johnson&rft.contributor=Gupta%2C+Anup&rft.date=2005-04&rft.type=Journal+(Paginated)&rft.type=PeerReviewed&rft.format=text%2Fhtml&rft.identifier=http%3A%2F%2Fcogprints.org%2F4219%2F1%2Fsrivathsan.htm&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F4219%2F2%2Fsrivathsan.pdf&rft.identifier=++Srivathsan%2C+Komandoor+and+Lester%2C+Steven+J+and+Appleton%2C+Christopher+P+and+Scott%2C+Luis+R+P+and+Munger%2C+Thomas+M++(2005)+Ventricular+Tachycardia+in+the+Absence+of+Structural+Heart+Disease.++%5BJournal+(Paginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F4219%2F