TY - GEN ID - cogprints4330 UR - http://cogprints.org/4330/ A1 - Levine, Paul A. Y1 - 2001/01// N2 - Since the introduction of steroid eluting electrodes, the incidence of an early massive rise in the capture threshold that either exceeds or threatens to exceed the programmed output of the pacemaker has declined but has not totally disappeared1 If a persistent or massive threshold rise is encountered in the days to months post-implant, one consideration is microinstability of the lead. In this setting, there may be a change in the morphology of the pacemaker evoked depolarization on the ECG or a change in the physical location of the lead as assessed with a chest x-ray. Another marker is fluctuations in the capture threshold on repeated assessments at the same office or clinic visit. The options for this problem include an operative procedure to reposition or replace the lead or to closely observe the patient hoping that the lead settles into a secure location. Another potential totally reversible cause is the introduction of an new medication or herb. If the possible explanations for threshold increase cited above have been excluded and the high capture threshold is believed to be due to lead maturation, increasing the output or possible lead replacement or repositioning have been the usual options. PB - Indian Pacing and Electrophysiology Group KW - Acute Massive Rise in Capture Threshold; pacemaker TI - Management of the Patient with an Acute Massive Rise in the Capture Threshold AV - public ER -