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--- abstract: 'It has frequently been suggested that some of the enduring subtle cognitive impairments seen in sober alcohol-dependent persons may be a result of sub-clinical liver dysfunction. Cognitive performance and liver function among 85 recently abstinent alcohol-dependent persons were assessed by means of a neuropsychological examination and the GGT test of liver function. Unlike some previous studies, no relationships were found between the two areas of functioning. It is argued that lack of statistical power did not account for the failure to find an association between the two domains. The proposition that residual cognitive impairment in abstinent alcoholic persons is (partly) mediated by earlier liver dysfunction rests on slight empirical foundations and remains speculative.' altloc: - http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6VC9-4CPVJXG-1-1&_cdi=5949&_user=1047984&_orig=browse&_coverDate=02%2F28%2F2005&_sk=999699997&view=c&wchp=dGLbVlz-zSkzV&md5=4e2f2900911b8fecf071e40410b20296&ie=/sdarticle.pdf chapter: ~ commentary: ~ commref: ~ confdates: ~ conference: ~ confloc: ~ contact_email: ~ creators_id: [] creators_name: - family: O'Mahony given: John F honourific: Dr lineage: '' date: 2005 date_type: published datestamp: 2005-06-19 department: ~ dir: disk0/00/00/43/87 edit_lock_since: ~ edit_lock_until: ~ edit_lock_user: ~ editors_id: [] editors_name: - family: Miller given: Peter M honourific: Dr lineage: '' eprint_status: archive eprintid: 4387 fileinfo: /style/images/fileicons/application_pdf.png;/4387/1/Cognitive_performance_and_liver_function_among_recently_abstinent_alcohol_abusers2005.pdf full_text_status: public importid: ~ institution: ~ isbn: ~ ispublished: pub issn: ~ item_issues_comment: [] item_issues_count: 0 item_issues_description: [] item_issues_id: [] item_issues_reported_by: [] item_issues_resolved_by: [] item_issues_status: [] item_issues_timestamp: [] item_issues_type: [] keywords: Cognitive impairment; liver function; alcohol abuse lastmod: 2011-03-11 08:56:04 latitude: ~ longitude: ~ metadata_visibility: show note: ~ number: 2 pagerange: 369-373 pubdom: FALSE publication: Journal of Addictive Behaviors publisher: Elsevier refereed: TRUE referencetext: | Chelune, G.J., & Parker, J. B. (1981). Neuropsychological deficits associated with chronic alcohol abuse. Clinical Psychology Review, 1, 181-195. Cohen, J. (1992). A power primer. Psychological Bulletin, 112, 155-159. Irwin, M., Smith, T. L., Butters, N., Brown, S., Baird, S., Grant, I., & Schuckit, M. A. (1989). Graded neuropsychological impairment and elevated g-glutamyl transferase in chronic alcoholic men. Alcoholism: Clinical and Experimental Research, 13, 99-103. Richardson, E. D., Malloy, P. F., Longabaugh, R., Williams, J., Noel, N., & Beattie, M. C. (1991). Liver function tests and neuropsychological impairment in substance abusers. Addictive Behaviors, 16, 51-55. Russell, E. W. (1988). Renorming Russell’s version of the Wechsler Memory Scale. Journal of Clinical and Experimental Neuropsychology, 40, 235-249. Schafer, K., Butters, N., Smith, T., Irwin, M., Brown, S., Hanger, P., Grant, I., & Schuckit, M. (1991). Cognitive performance of alcoholics: A longitudinal evaluation of the role of drinking history, depression, liver function, nutrition and family history. Alcoholism: Clinical and Experimental Research, 15, 653-660. Stevens, J. (1992). Applied multivariate statistics for the social sciences. (2nd ed.). Hillsdale: NJ, Lawrence Erlbaum Walton, N. H., & Bowden, S. C. (1997). Does liver dysfunction explain neuropsychological status in recently detoxified alcohol-dependent clients? Alcohol and Alcoholism, 32, 287-295. relation_type: [] relation_uri: [] reportno: ~ rev_number: 12 series: ~ source: ~ status_changed: 2007-09-12 16:59:25 subjects: - neuro-psy - neuro-psych succeeds: ~ suggestions: ~ sword_depositor: ~ sword_slug: ~ thesistype: ~ title: Cognitive Performance and Liver Function among Recently Abstinent Alcohol Abusers type: journalp userid: 5642 volume: 30