?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Impact+of+a+Right+Ventricular+Impedance+Sensor+on+the+Cardiovascular+Responses+to+Exercise+in+Pacemaker+Dependent+Patients&rft.creator=Linnea%2C+Cook&rft.creator=Corey%2C+Tomczak&rft.creator=Edward%2C+Busse&rft.creator=Tada%2C+Hiroshi&rft.creator=John%2C+Tsang&rft.creator=Wladyslaw%2C+Wojcik&rft.creator=Robert%2C+Haennel&rft.subject=Indian+Pacing+and+Electrophysiology+Journal&rft.description=Background.+The+evaluation+of+the+heart+rate+(HR)+response+to+exercise+is+important+for+the+assessment+of+the+rate+response+algorithm+of+sensor-controlled+pacemakers.+This+study+examined+the+effects+of+a+right+ventricular+impedance+sensor+driven+pacemaker+on+the+cardiovascular+responses+to+incremental+exercise+in+pacemaker+dependent+patients.+%0AMethods.+Twelve+patients+(70.5+%C2%B1+9.5+years%3B+5+Females%3A+7+Males)+implanted+with+an+Inos2%2B++closed+loop+stimulation+(CLS)+pacemaker+were+compared+to+12+healthy+age+and+sex+matched+controls+(70.6+%C2%B1+4.8+years).+All+subjects+performed+the+chronotropic+assessment+exercise+protocol+(CAEP).+Variables+of+interest+included+HR%2C+cardiac+output+(Q)%2C+oxygen+uptake+(Vo2)+and+blood+pressure+(BP).++Data+were+analyzed+at+rest%2C+throughout+exercise+and+during+recovery.+Furthermore%2C+patient+chronotropic+responses+were+compared+to+a+reference+chronotropic+response+slope+for+aerobic+exercise.+%0AResults.+There+were+no+differences+between+groups+for+HR+or+Q.+response+throughout+exercise.+At+peak+exercise%2C+V.o2+(mL.kg-1.min-1)+was+higher+for+the+controls+(p+%3C+0.05).+The+patient+chronotropic+response+slope+was+comparable+to+the+CAEP+reference+slope+from+rest+to+both+the+anaerobic+threshold+(AT)+and+peak+exercise.++During+recovery%2C+no+differences+were+observed+between+the+groups+for+any+parameters+or+for+the+HR+decay+slopes.+%0AConclusions.+Up+to+the+anaerobic+threshold%2C+the+right+ventricular+impedance+sensor+driven+pacemaker+delivered+a+pacing+rate+that+contributed+to+an+overall+cardiovascular+response+similar+to+that+observed+in+healthy+age+matched+subjects.%0A&rft.publisher=Indian+Pacing+and+Electrophysiology+Group&rft.contributor=Singh%2C+Balbir&rft.contributor=Lokhandwala%2C+Yash&rft.contributor=Francis%2C+Johnson&rft.contributor=Gupta%2C+Anup&rft.date=2005-07&rft.type=Journal+(Paginated)&rft.type=PeerReviewed&rft.format=text%2Fhtml&rft.identifier=http%3A%2F%2Fcogprints.org%2F4487%2F1%2Fhaennel.htm&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F4487%2F2%2Fhaennel.pdf&rft.identifier=++Linnea%2C+Cook+and+Corey%2C+Tomczak+and+Edward%2C+Busse+and+Tada%2C+Hiroshi+and+John%2C+Tsang+and+Wladyslaw%2C+Wojcik+and+Robert%2C+Haennel++(2005)+Impact+of+a+Right+Ventricular+Impedance+Sensor+on+the+Cardiovascular+Responses+to+Exercise+in+Pacemaker+Dependent+Patients.++%5BJournal+(Paginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F4487%2F