title: Arrhythmias After Tetralogy of Fallot Repair creator: Folino, Antonio Franco creator: Daliento, Luciano subject: Indian Pacing and Electrophysiology Journal description: Tetralogy of Fallot is the most common cyanotic congenital heart disease, with a good outcome after total surgical correction. In spite of a low perioperative mortality and a good quality of life, late sudden death remains a significant clinical problem, mainly related to episodes of sustained ventricular tachycardia and ventricular fibrillation. Fibro-fatty substitution around infundibular resection, intraventricular septal scar, and patchy myocardial fibrosis, may provide anatomical substrates of abnormal depolarization and repolarization causing reentrant ventricular arrhythmias. Several non-invasive indices based on classical examination such as ECG, signal-averaging ECG, and echocardiography have been proposed to identify patients at high risk of sudden death, with hopeful results. In the last years other more sophisticated invasive and non-invasive tools, such as heart rate variability, electroanatomic mapping and cardiac magnetic resonance added a relevant contribution to risk stratification. Even if each method per se is affected by some limitations, a comprehensive multifactorial clinical and investigative examination can provide an accurate risk evaluation for every patient publisher: Indian Pacing and Electrophysiology Group contributor: Singh, Balbir contributor: Lokhandwala, Yash contributor: Francis, Johnson contributor: Gupta, Anup date: 2005-10 type: Journal (Paginated) type: PeerReviewed format: text/html identifier: http://cogprints.org/4598/1/folino.htm format: application/pdf identifier: http://cogprints.org/4598/2/folino.pdf identifier: Folino, Antonio Franco and Daliento, Luciano (2005) Arrhythmias After Tetralogy of Fallot Repair. [Journal (Paginated)] relation: http://cogprints.org/4598/