?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Predictors+of+appropriate+ICD+therapy+in+patients+with+implantable+cardioverter-defibrillator&rft.creator=Dehghani%2C+Mohammad+Reza&rft.creator=Arya%2C+Arash&rft.creator=Haghjoo%2C+Majid&rft.creator=Zahra%2C+Emkanjoo&rft.creator=Mohammad%2C+Alasti&rft.creator=Babak%2C+Kazemi&rft.creator=Nikoo%2C+Mohammad+Hosein&rft.creator=Sadr-Ameli%2C+Mohammad+Ali&rft.subject=Indian+Pacing+and+Electrophysiology+Journal&rft.description=Background%3A+Understanding+the+predictors+of+appropriate+implantable+cardioverter+defibrillator+(ICD)+therapy+could+help+to+better+identify+candidates+for+ICD+implantation.%0A%0AMethods%3A+One+hundred+and+sixty+two+patients+with+ICD+(111+with+coronary+artery+disease+%5BCAD%5D+and+51+with+dilated+cardiomyopathy+%5BDCM%5D)+were+included+in+the+study.+Clinical%2C+electrocardiographic%2C+and+ICD+stored+data+and+electrograms+were+collected.+%0A%0AResults%3A+During+mean+follow+up+of+15%C2%B111+months+54+patients+(33%25)+received+%E2%89%A5+1+appropriate+ICD+therapy+(AICDT).+We+used+binary+logistic+regression+analysis+with+forward+selection+method+to+find+the+potential+predictors+of+appropriate+ICD+therapy+after+device+implantation.+Male+gender+(odds+ratio+%5BOR%5D+%3D+2.76%2C+95%25+confidence+interval+%5BCI%5D+%3D+1.1+%E2%80%93+7.1%2C+P%3D0.021)%2C+DCM+as+underlying+heart+disease+(OR+%3D+4.2%2C+95%25+CI+%3D+1.9+%E2%80%93+9.5%2C+P%3D0.001)%2C+and+QRS+width+%3E+100+ms+(OR+%3D+2.58%2C+95%25+CI+%3D+1.2+%E2%80%93+5.4%2C+P%3D0.010)+were+correlated+with+increased+likelihood+of+AICDT+during+the+follow+up+period.+In+subgroup+analysis+of+the+patients+with+CAD+and+DCM%2C+QRS+duration+%3E+100+ms+was+correlated+with+the+probability+of+%E2%89%A5+1+AICDT.+In+our+patients+indication+of+ICD+implantation+(primary+versus+secondary+prevention)+did+not+influence+probability+of+%E2%89%A5+1+AICDT+(adjusted+OR+%3D+1.66%2C+95%25+CI+%3D+0.7+%E2%80%93+4.0%2C+Mantel-Haenszel+P+value+P%3D0.355.)%0A%0AConclusion%3A+QRS+width+could+be+used+as+an+additional+simple+risk+stratifier+beyond+EF+to+identify+potential+candidates+who+would+benefit+more+from+ICD+implantation.+This+may+have+practical+implications+for+patient+selection+especially+in+developing+countries.+Indication+of+ICD+implantation+(primary+versus+secondary+prevention)+did+not+affect+the+probability+of+%E2%89%A5+1+AICDT+during+the+follow+up+period.+%0A&rft.publisher=Indian+Pacing+and+Electrophysiology+Group&rft.contributor=Singh%2C+Balbir&rft.contributor=Lokhandwala%2C+Yash&rft.contributor=Francis%2C+Johnson&rft.contributor=Gupta%2C+Anup&rft.date=2006-01&rft.type=Journal+(Paginated)&rft.type=PeerReviewed&rft.format=text%2Fhtml&rft.identifier=http%3A%2F%2Fcogprints.org%2F4673%2F1%2Farya2.htm&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F4673%2F2%2Farya2.pdf&rft.identifier=++Dehghani%2C+Mohammad+Reza+and+Arya%2C+Arash+and+Haghjoo%2C+Majid+and+Zahra%2C+Emkanjoo+and+Mohammad%2C+Alasti+and+Babak%2C+Kazemi+and+Nikoo%2C+Mohammad+Hosein+and+Sadr-Ameli%2C+Mohammad+Ali++(2006)+Predictors+of+appropriate+ICD+therapy+in+patients+with+implantable+cardioverter-defibrillator.++%5BJournal+(Paginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F4673%2F