@misc{cogprints4700, volume = {4}, number = {3}, month = {November}, author = {Omalu I CJ and Yako A B and Duhlinska D D and Anyanwu G I and Pam V A and Inyama P U}, editor = {Dr. Srinivas Kakkilaya Bevinje}, title = {First detection of intestinal microsporidia in Northern Nigeria}, publisher = {Dr. B.S. Kakkilaya}, year = {2005}, journal = {Online Journal Of Health And Allied Sciences}, keywords = {Enterocytozoon bienuesi, Encephalitozoon intestinalis, Microsporidial infections}, url = {http://cogprints.org/4700/}, abstract = {Microsporidia are intracellular spore-forming protozoa that are increasingly being recognized as pathogens in humans. Faecal samples were taken from 2250 HIV/AIDS and 1050 HIV-negative patients from Kano and Makurdi in Northern Nigeria, and were investigated for microsporidial infections by Giemsa staining technique (Light microscopy). In Kano, Enterocytozoon bienuesi was detected in 8 (14.17\%) and Encephalitozoon intestinalis in 5 (2.60\%) out of 192 HIV/AIDS patients screened. A mixed infection of both 0.52\% was observed. Results from Makurdi showed that Enterocytozoon bienuesi was detected in 13 (0.65\%) and Encephalitozoon intestinalis in 96 (4.78\%) out of 2008 HIV/AIDS patients examined. No mixed infection was observed. Microsporidial spores were not found in 1050 HIV-negative patients screened from both areas. There was a significant difference (X2, p{\ensuremath{<}}0.05) in infection rates between the HIV/AIDS and HIV-negative patients. This study aimed at detecting the prevalence of intestinal microsporidia to provide baseline data on the status of this disease in Nigeria. Detection of Microsporidia in Immuno-compromised patients has not been described previously in this area.} }