@misc{cogprints4803, volume = {6}, number = {2}, month = {April}, author = {Mark D O?Neill and Pierre Ja{\"i}s and Anders J{\"o}nsson and Yoshihide Takahashi and Fr{\'e}d{\'e}ric Sacher and M{\'e}l{\`e}ze Hocini and Prashanthan Sanders and Thomas Rostock and Martin Rotter and Jacques Cl{\'e}menty and Michel Ha{\"i}ssaguerre}, editor = {Balbir Singh and Yash Lokhandwala and Johnson Francis and Anup Gupta and Joydeep Ghosh}, title = {An Approach to Catheter Ablation of Cavotricuspid Isthmus Dependent Atrial Flutter}, publisher = {Indian Pacing and Electrophysiology Group}, year = {2006}, journal = {Indian Pacing and Electrophysiology Journal}, pages = {100--110}, keywords = {Atrial flutter; cavotricuspid isthmus; ablation }, url = {http://cogprints.org/4803/}, abstract = { Much of our understanding of the mechanisms of macro re-entrant atrial tachycardia comes from study of cavotricuspid isthmus (CTI) dependent atrial flutter. In the majority of cases, the diagnosis can be made from simple analysis of the surface ECG. Endocardial mapping during tachycardia allows confirmation of the macro re-entrant circuit within the right atrium while, at the same time, permitting curative catheter ablation targeting the critical isthmus of tissue located between the tricuspid annulus and the inferior vena cava. The procedure is short, safe and by demonstration of an electrophysiological endpoint - bidirectional conduction block across the CTI - is associated with an excellent outcome following ablation. It is now fair to say that catheter ablation should be considered as a first line therapy for patients with documented CTI-dependent atrial flutter.} }