title: An Approach to Catheter Ablation of Cavotricuspid Isthmus Dependent Atrial Flutter creator: O’Neill, Mark D creator: Jaïs, Pierre creator: Jönsson, Anders creator: Takahashi, Yoshihide creator: Sacher, Frédéric creator: Hocini, Mélèze creator: Sanders, Prashanthan creator: Rostock, Thomas creator: Rotter, Martin creator: Clémenty, Jacques creator: Haïssaguerre, Michel subject: Indian Pacing and Electrophysiology Journal description: Much of our understanding of the mechanisms of macro re-entrant atrial tachycardia comes from study of cavotricuspid isthmus (CTI) dependent atrial flutter. In the majority of cases, the diagnosis can be made from simple analysis of the surface ECG. Endocardial mapping during tachycardia allows confirmation of the macro re-entrant circuit within the right atrium while, at the same time, permitting curative catheter ablation targeting the critical isthmus of tissue located between the tricuspid annulus and the inferior vena cava. The procedure is short, safe and by demonstration of an electrophysiological endpoint - bidirectional conduction block across the CTI - is associated with an excellent outcome following ablation. It is now fair to say that catheter ablation should be considered as a first line therapy for patients with documented CTI-dependent atrial flutter. publisher: Indian Pacing and Electrophysiology Group contributor: Singh, Balbir contributor: Lokhandwala, Yash contributor: Francis, Johnson contributor: Gupta, Anup contributor: Ghosh, Joydeep date: 2006-04 type: Journal (Paginated) type: PeerReviewed format: text/html identifier: http://cogprints.org/4803/1/ONeill.htm format: text/html identifier: http://cogprints.org/4803/2/ONeill.pdf identifier: O’Neill, Mark D and Jaïs, Pierre and Jönsson, Anders and Takahashi, Yoshihide and Sacher, Frédéric and Hocini, Mélèze and Sanders, Prashanthan and Rostock, Thomas and Rotter, Martin and Clémenty, Jacques and Haïssaguerre, Michel (2006) An Approach to Catheter Ablation of Cavotricuspid Isthmus Dependent Atrial Flutter. [Journal (Paginated)] relation: http://cogprints.org/4803/