?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Effect+Of+Oestradiol+On+Mouse+Vaginal+Epithelium&rft.creator=Shetty%2C+Dr.+Prakash&rft.creator=Prabhu+V%2C+Dr.+Latha&rft.creator=Pai+M%2C+Dr.+Mangala&rft.subject=Online+Journal+of+Health+and+Allied+Sciences&rft.description=Oestradiol+which+induces+the+proliferation+of+the+vaginal+epithelium+is+used+in+the+oestrogen+replacement+therapy+for+menopausal+and+postmenopausal+disorders.+The+exact+onset+of+induced+cell+proliferation+and+recovery+to+the+controlled+level+has+not+been+reported+before.+Hence+this+study+was+done+in+ovariectomised+mice+and+the+period+of+cellular+response+to+ethinyl+estradiol%2C+a+semisynthetic+ester+(0.025mg%2Fkg)+was+recorded.+The+vaginal+epithelium+was+studied+for+histological+changes+and+incidence+of+mitotic+figures.+The+onset+of+proliferation+started+at+4h+after+exposure+and+reached+its+maximum+at+32h+and+declined+gradually+thereafter+to+reach+the+base+level+at+60h.&rft.publisher=Dr.+B.S.+Kakkilaya&rft.contributor=Kakkilaya+Bevinje%2C+Dr.+Srinivas&rft.date=2006-03&rft.type=Journal+(On-line%2FUnpaginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F4848%2F1%2F2005-4-1.pdf&rft.identifier=++Shetty%2C+Dr.+Prakash+and+Prabhu+V%2C+Dr.+Latha+and+Pai+M%2C+Dr.+Mangala++(2006)+Effect+Of+Oestradiol+On+Mouse+Vaginal+Epithelium.++%5BJournal+(On-line%2FUnpaginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F4848%2F