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abstract: |
Background
Hashimoto’s thyroiditis is one of the most common causes of hypothyroidism. Hypothyroidism is a known cause of hyperlipidemia. There is a strong correlation between coronary and mesenteric vessel atherosclerosis. Acute mesenteric ischemia is a cause of intestinal hemorrhagic infarction.
Case history
We present an autopsy case of 35-year-old male who presented with features of obstruction and edema with previously undetected hypothyroidism.
Conclusion
Hypothyroidism associated with atherosclerosis can lead to fatal intestinal gangrene as corroborated by this autopsy case.
Key words –Hypothyroidism, intestinal gangrene, autopsy, atherosclerosis
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creators_id:
- rashmipatnayak2002@yahoo.co.in
- arunaprayaga56@yahoo.com
- Raj28dr@yahoo.co.in
- anuradhasvn@yahoo.co.in
- jayashankar24@yahoo.co.in
creators_name:
- family: Patnayak
given: Rashmi Patnayak
honourific: ''
lineage: ''
- family: Prayaga
given: Aruna K. Prayaga
honourific: ''
lineage: ''
- family: Reddy
given: Rajasekhar Reddy
honourific: ''
lineage: ''
- family: S.V.N.
given: S.V.N. Anuradha
honourific: ''
lineage: ''
- family: E.
given: E.Jayashankar
honourific: ''
lineage: ''
date: 2006
date_type: published
datestamp: 2006-07-23
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dir: disk0/00/00/50/10
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eprintid: 5010
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full_text_status: public
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ispublished: unpub
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lastmod: 2011-03-11 08:56:32
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number: 3
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pubdom: FALSE
publication: Calicut Medical Journal
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refereed: FALSE
referencetext: |
1. Cecilia M. Fenoglio-Preiser, Amy E. Noffsinger, Grant N. Stemmermann, Patrick E. Lantz, Margaret B. Listrom, Franco O. Rilke.Nonneoplastic lesions of the small intestine. In: Gastrointestinal Pathology, eds.2nd edition. Philadelphia, Lippincott-Raven, 1998,341-3482. Stassi G, De Maria R: Autoimmune thyroid disease: new models of cell death in autoimmunity. Nat Rev Immunol2 (3): 195-204,2002
3. Pearce EN, Farwell AP, Braverman LE: Thyroiditis Engl J Med 348:2646,2003
4. Thompson GR, Soutar AK, Spengel FA, Jadhav A, Gavigan SJ, Myant NB 1981 Defects of receptor-mediated low density lipoprotein catabolism in homozygous familial hypercholesterolemia and hypothyroidism in vivo. Proc Natl Acad Sci USA 78:2591–2595
5. Steinberg AD.Myxedema and coronary artery disease: a comparative autopsy study. Ann Intern Med 1968; 68:338 – 344.
6. Bergus. GR, Randall. C, Van.Peursem.R, Lack of association between hypertension and hypothyroidism in a primary care setting Hum Hypertens. 1999; 13:231 – 5.
7. Bergus. GR, Randall. C, Van.Peursem.R, Lack of association between hypertension and hypothyroidism in post-menopausal women in a primary care setting AM Board – Fam – Pract.1997; 10:185-01.
8. Jrven O, Laurika J, Salenius JP, Tarkka M, Acute intestinal ischemia: a review of 214 cases .Ann Chir Gynaecol 1994; 83:22-25
9. Reinus JF, Brandt LJ, Boley SJ.Ischemic disease of the bowel. Gastroenterol Clin North Am 1990; 19:319-343
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rev_number: 12
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status_changed: 2007-09-12 17:06:10
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- calcut
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title: 'An intriguing autopsy case of gangrene intestine '
type: journale
userid: 6573
volume: 4