--- abstract: |- Hypothyroidism, or myxedema, is the clinical syndrome that results from decreased production of T4 and T3.Most patients have primary hypothyroidism .The etiology of adult primary hypothyroidism includes autoimmune hypothyroidism (Hashimoto’s thyroiditis), post – ablation after radio-active iodine, thyroid surgery and drugs such as Amiodarone and Lithium. Manifestations are variable and proportionate to the degree and duration of thyroid hormone deficiency as well as age of onset. The presence of goiter is common in younger patients (Hashimoto’s) but often absent in the elderly. Clinical features of hypothyroidism are insidious and often missed, particularly in the elderly. altloc: [] chapter: ~ commentary: ~ commref: ~ confdates: ~ conference: ~ confloc: ~ contact_email: ~ creators_id: [] creators_name: - family: Patnayak given: Rashmi honourific: '' lineage: '' - family: Prayaga given: Aruna honourific: '' lineage: '' - family: Reddy given: Rajasekhar honourific: '' lineage: '' - family: S.V.N. given: Anuradha honourific: '' lineage: '' - family: E given: Jayasankar honourific: '' lineage: '' date: 2006 date_type: published datestamp: 2006-09-01 department: ~ dir: disk0/00/00/50/91 edit_lock_since: ~ edit_lock_until: ~ edit_lock_user: ~ editors_id: [] editors_name: [] eprint_status: archive eprintid: 5091 fileinfo: /style/images/fileicons/application_pdf.png;/5091/1/e3.pdf full_text_status: public importid: ~ institution: ~ isbn: ~ ispublished: pub issn: ~ item_issues_comment: [] item_issues_count: 0 item_issues_description: [] item_issues_id: [] item_issues_reported_by: [] item_issues_resolved_by: [] item_issues_status: [] item_issues_timestamp: [] item_issues_type: [] keywords: ~ lastmod: 2011-03-11 08:56:34 latitude: ~ longitude: ~ metadata_visibility: show note: ~ number: 3 pagerange: ~ pubdom: TRUE publication: Calicut Medical Journal publisher: Calicut Medical College Alumni Association refereed: TRUE referencetext: |- 1. Cecilia M. Fenoglio-Preiser, Amy E. Noffsinger, Grant N. Stemmermann, Patrick E. Lantz, Margaret B. Listrom, Franco O. Rilke.Nonneoplastic lesions of the small intestine. In: Gastrointestinal Pathology, eds.2nd edition. Philadelphia, Lippincott-Raven, 1998,341-348 Patnayak et al Calicut Medical Journal 2006;4(3):e3 Page 4 (Page number not for indexing purposes) 2. Stassi G, De Maria R: Autoimmune thyroid disease: new models of cell death in autoimmunity. Nat Rev Immunol2 (3): 195-204,2002 3. Pearce EN, Farwell AP, Braverman LE: Thyroiditis Engl J Med 348:2646,2003 4. Thompson GR, Soutar AK, Spengel FA, Jadhav A, Gavigan SJ, Myant NB 1981 Defects of receptor-mediated low density lipoprotein catabolism in homozygous familial hypercholesterolemia and hypothyroidism in vivo. Proc Natl Acad Sci USA 78:2591–2595 5. Steinberg AD.Myxedema and coronary artery disease: a comparative autopsy study. Ann Intern Med 1968; 68:338 – 344. 6. Bergus. GR, Randall. C, Van.Peursem.R, Lack of association between hypertension and hypothyroidism in a primary care setting Hum Hypertens. 1999; 13:231 – 5. 7. Bergus. GR, Randall. C, Van.Peursem.R, Lack of association between hypertension and hypothyroidism in post-menopausal women in a primary care setting AM Board – Fam – Pract.1997; 10:185-01. 8. Jrven O, Laurika J, Salenius JP, Tarkka M, Acute intestinal ischemia: a review of 214 cases .Ann Chir Gynaecol 1994; 83:22-25 9. Reinus JF, Brandt LJ, Boley SJ.Ischemic disease of the bowel. Gastroenterol Clin North Am 1990; 19:319-343 relation_type: [] relation_uri: [] reportno: ~ rev_number: 12 series: ~ source: ~ status_changed: 2007-09-12 17:06:55 subjects: - calcut succeeds: ~ suggestions: ~ sword_depositor: ~ sword_slug: ~ thesistype: ~ title: An intriguing autopsy case of gangrene intestine type: journale userid: 4187 volume: 4