%A Dr. Oliver Grimm
%A Dr. Petra Hubrich
%T Delusional Belief induced by clomiphene treatment
%X We report the case of a 35 year old women who developed a complex paranoid delusion during the course of clomiphene treatment f?r ovulation. The psychopathology was remarkable, because after a short hypomanic period the patient was without severe cognitive disturbance but struggled with a complex monothematic delusion. The delusion vanished in the course of a combination treatment with olanzapine a cognitive behavioral therapy. We could not entirely rule out the possibility of an endogenous psychiatric disease but nevertheless we encountered an unusual monothematic delusion which showed a strong temporal correlation with the intake of clomiphene. We provide some speculation about underlying neurobiological mechanisms on the basis of the dopamine theory of delusion.
%D 2006
%K estrogene, clomiphene, psychosis, delusion
%L cogprints5095

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