creators_name: Bapi, Raju S. creators_name: Pammi, V. S. Chandrasekhar creators_name: Miyapuram, K. P. editors_name: Singh, Nandini type: confposter datestamp: 2006-09-17 lastmod: 2011-03-11 08:56:36 metadata_visibility: show title: Methods and Approaches for Characterizing Learning Related Changes Observed in functional MRI Data — A Review ispublished: pub subjects: brain-img full_text_status: public keywords: General Linear Model, Learning, SPM, modelling HRF, time series analysis, ICA abstract: Brain imaging data have so far revealed a wealth of information about neuronal circuits involved in higher mental functions like memory, attention, emotion, language etc. Our efforts are toward understanding the learning related effects in brain activity during the acquisition of visuo-motor sequential skills. The aim of this paper is to survey various methods and approaches of analysis that allow the characterization of learning related changes in fMRI data. Traditional imaging analysis using the Statistical Parametric Map (SPM) approach averages out temporal changes and presents overall differences between different stages of learning. We outline other potential approaches for revealing learning effects such as statistical time series analysis, modelling of haemodynamic response function and independent component analysis. We present example case studies from our visuo-motor sequence learning experiments to describe application of SPM and statistical time series analyses. Our review highlights that the problem of characterizing learning induced changes in fMRI data remains an interesting and challenging open research problem. date: 2003 date_type: published pagerange: 221-229 refereed: FALSE referencetext: Bapi RS, Doya K, Harner AM (2000a) Evidence for effector independent representations and their differential time course of acquisition during motor sequence learning. Exp Brain Res 132:149–162. 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Volkow ND, Rosen B, Farde L (1997) Imaging the living human brain: Magnetic resonance imaging and positron emission tomography. Proc Natl Acad Sci USA 94:2787–2788. citation: Bapi, Raju S. and Pammi, V. S. Chandrasekhar and Miyapuram, K. P. (2003) Methods and Approaches for Characterizing Learning Related Changes Observed in functional MRI Data — A Review. [Conference Poster] document_url: http://cogprints.org/5145/1/Bapi_ICTN_final.pdf