@misc{cogprints5169, volume = {5}, number = {2}, month = {September}, author = {Chigozie Uneke Jesse and Ogbonnaya Ogbu and Moses Alo and Thaddeus Ariom}, editor = {Dr. Srinivas Kakkilaya Bevinje and Dr. Shatharam Baliga B}, title = {Syphilis serology in HIV-positive and HIV-negative Nigerians: The public health significance}, publisher = {Dr. B.S. Kakkilaya}, year = {2006}, journal = {Online Journal Of Health And Allied Sciences}, keywords = {Syphilis, Treponema pallidum, HIV, Seroprevalence}, url = {http://cogprints.org/5169/}, abstract = {Syphilis has acquired new potential for morbidity and mortality through association with increased risk for HIV infection. Case-control survey was conducted using Rapid Plasma Reagin test and confirmatory Immunochromatographic test among HIV-positive (cases) and HIV-negative (control) Nigerians. A total of 35(14.0\%) of 250 HIV-positive and 5(2.0\%) of 250 HIV-negative individuals studied were seropositive for syphilis, the difference was statistically significant (P{\ensuremath{<}}0.05). The prevalence was higher among females than males of HIV-positive (15.0\% versus 12.7\%) and of the HIV-negative (2.1\% versus 1.9\%) individuals. Syphilis seroprevalence was highest among HIV-positive individuals aged 21-30 years (20.5\%) and 41-50 years old HIV-negative individuals (4.5\%). Sex education, promotion of safer sexual behaviour, prompt diagnosis of STDs and provision of effective, accessible treatment are recommended} }