?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Quality+of+Life+in+Patients+with+Implantable+Cardioverter+Defibrillators%0A&rft.creator=Francis%2C+Johnson&rft.creator=Johnson%2C+Beena&rft.creator=Niehaus%2C+Michael&rft.subject=Indian+Pacing+and+Electrophysiology+Journal&rft.description=Background%3A+The+implantable+cardioverter+defibrillator+(ICD)+is+a+life+saving+device+for+individuals+with+life+threatening+ventricular+arrhythmias.+There+is+no+doubt+that+it+is+a+cost+effective+therapy+in+various+congenital+and+acquired+arrhythmogenic+disorders.+Nevertheless%2C+shock+delivery+may+be+painful+and+frightening+which+causes+psychological+distress+and+deterioration+of+perceived+quality+of+life.+%0A%0AMethods%3A+A+systematic+meta-analysis+on+studies+reporting+quality+of+life+in+patients+implanted+with+ICDs+was+done+using+professional+databases.+Related+articles+and+references+of+the+relevant+articles+were+also+searched+for+suitable+studies.%0A%0AResults%3A+Thirty+studies+with+a+total+of+3412+patients+on+implantable+defibrillators+were+identified.+Five+of+them+were+large+randomised+studies+with+a+total+of+1680+patients%2C+while+25+were+non-randomised+studies.+Medical+Outcome+Study+36-item+Short+Form+health+survey+(SF+-+36)+was+the+most+common+instrument+used+for+assessment+of+quality+of+life.+Only+one+of+the+5+major+randomised+trial+reported+worsening+of+quality+of+life+after+implantation+of+a+defibrillator.+In+the+subgroup+of+patients+receiving+shocks%2C+three+out+of+the+five+trials+reported+worsening+of+quality+of+life.%0A%0ASummary%3A+Most+of+the+randomised+studies+showed+either+neutral+or+better+quality+of+life+in+patients+on+implantable+defibrillators.+In+the+subset+of+patients+receiving+shocks%2C+worsening+of+quality+of+life+was+found+in+most+randomised+studies.+Therefore%2C+activation+of+antitachycardia+pacing+should+be+performed+in+every+ICD-patient+in+order+to+miminze+painful+shocks+and+consequent+deterioration+of+quality+of+life.%0A&rft.publisher=Indian+Pacing+and+Electrophysiology+Group&rft.contributor=Singh%2C+Balbir&rft.contributor=Lokhandwala%2C+Yash&rft.contributor=Francis%2C+Johnson&rft.contributor=Gupta%2C+Anup&rft.contributor=Ghosh%2C+Joydeep&rft.date=2006-07&rft.type=Journal+(Paginated)&rft.type=PeerReviewed&rft.format=text%2Fhtml&rft.identifier=http%3A%2F%2Fcogprints.org%2F5237%2F1%2Ffrancis6.htm&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F5237%2F2%2Ffrancis6.pdf&rft.identifier=++Francis%2C+Johnson+and+Johnson%2C+Beena+and+Niehaus%2C+Michael++(2006)+Quality+of+Life+in+Patients+with+Implantable+Cardioverter+Defibrillators.++%5BJournal+(Paginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F5237%2F