?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Human+Microsporidial+Infections&rft.creator=I+CJ%2C+Omalu&rft.creator=D+D%2C+Duhlinska&rft.creator=G+I%2C+Anyanwu&rft.creator=V+A%2C+Pam&rft.creator=P+U%2C+Inyama&rft.subject=Online+Journal+of+Health+and+Allied+Sciences&rft.description=Microsporidia+are+eukaryotic%2C+spore+forming+obligate+intracellular+parasites%2C+first+recognised+over+100+years+ago.+Microsporidia+are+becoming+increasingly+recognised+as+infectious+pathogens+causing+intestinal+and+extra-intestinal+diseases+in+both+immuno-competent+and+immuno-suppressed+patients.+They+are+characterised+by+the+production+of+resistant+spores+that+vary+in+size+depending+on+the+species%3B+and+poses+a+unique+organelle%2C+the+polar+tubule+(polar+filament)%2C+which+is+coiled+inside+the+spore+as+demonstrated+by+its+ultra+structure.+Other+unusual+characteristics+are+the+lack+of+mitochondria+and+the+prokaryotic-like+ribosomes%2C+which+indicate+the+primitive+nature+of+the+group.+Presently+there+are+seven+genera%2C+Enterocytozoon%2C+Encephalitozoon%2C+Nosema%2C+Pleistophora%2C+Trachi+pleistophora%2C+Brachiola%2C+vittaforma+species+which+have+been+reported+from+human+hosts+as+agents+of+systemic%2C+ocular%2C+intestinal+and+muscular+infections%2C+are+described+and+the+diagnosis%2C+treatment%2C+and+source+of+infections+discussed.&rft.publisher=Dr.+B.S.+Kakkilaya&rft.contributor=Kakkilaya+Bevinje%2C+Dr.+Srinivas&rft.date=2006-12&rft.type=Journal+(On-line%2FUnpaginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F5321%2F1%2F2006-3-2.pdf&rft.identifier=++I+CJ%2C+Omalu+and+D+D%2C+Duhlinska+and+G+I%2C+Anyanwu+and+V+A%2C+Pam+and+P+U%2C+Inyama++(2006)+Human+Microsporidial+Infections.++%5BJournal+(On-line%2FUnpaginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F5321%2F