?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Study+on+the+effect+of+green+pit+viper+venom+(Trimeresurus+albolabris)+on+platelet+morphology+by+flow+cytometry&rft.creator=Soogarun%2C+Suphan&rft.creator=+Choewbamrungkiat%2C+Montri&rft.creator=+Wiwanitkit%2C+Viroj&rft.creator=Suwansaksri%2C+Jamsai&rft.creator=Nopanitaya%2C+Waykin&rft.creator=Pradniwat%2C+Paweena&rft.creator=Palasuwan%2C+Attakorn&rft.creator=Chanprasert%2C+Supantitra&rft.subject=Online+Journal+of+Health+and+Allied+Sciences&rft.description=The+incidence+of+venomous+snake+bites%2C+especially+by+green+pit+viper%2C+has+been+increasing+every+year+in+Thailand.+The+bite+of+green+pit+viper+causes+bleeding+because+of+thrombin%E2%80%93like+property+of+the+venom+and+it+has+been+reported+that+the+mean+platelet+volume+decreases+in+those+bitten+by+this+snake.+The+objective+of+this+study+was+to+study+the+effect+of+green+pit+viper+venom+(Trimeresurus+albolabris)+on+platelet+volume+(MPV)%2C+number+of+platelets+and+platelet+morphology+in+vitro.+The+test+was+carried+out+by+washing+platelet+in+phosphate+buffer+pH+7.2+so+as+to+get+rid+of+fibrinogen%2C+then+the+washed+platelets+were+mixed+with+green+pit+viper+venom.+The+mean+platelet+volume+and+number+of+platelets+were+determined+by+flow+cytometry.+The+results+showed+that+there+was+a+decrease+in+the+number+of+platelets+(216%C2%B1101+x+109%2Fl+and+78.1%C2%B143.4+x+109%2Fl%3B+P%3C+0.05)+and+also+the+MPV+(8.9%C2%B11.2fl+and+4.8%C2%B11.3fl%2C+P%3C+0.05).+The++platelet+size+was+smaller+than+normal%2C+ranging+from+1.1-1.2+micrometers.+In+conclusion%2C+the+green+pit+viper+venom+had+a+direct+effect+on+platelet+morphology%2C+especially+by+decreasing+platelet+volume+and+numbers.&rft.publisher=Dr.+B.S.+Kakkilaya&rft.contributor=Kakkilaya+Bevinje%2C+Dr.+Srinivas&rft.date=2006-12&rft.type=Journal+(On-line%2FUnpaginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F5327%2F1%2F2006-3-5.pdf&rft.identifier=++Soogarun%2C+Suphan+and++Choewbamrungkiat%2C+Montri+and++Wiwanitkit%2C+Viroj+and+Suwansaksri%2C+Jamsai+and+Nopanitaya%2C+Waykin+and+Pradniwat%2C+Paweena+and+Palasuwan%2C+Attakorn+and+Chanprasert%2C+Supantitra++(2006)+Study+on+the+effect+of+green+pit+viper+venom+(Trimeresurus+albolabris)+on+platelet+morphology+by+flow+cytometry.++%5BJournal+(On-line%2FUnpaginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F5327%2F