TY  - GEN
ID  - cogprints5764
UR  - http://cogprints.org/5764/
A1  - Kristal, Dr. Mark B.
A1  - Thompson, A. C.
A1  - Grishkat, H.L.
Y1  - 1985///
N2  - Analgesia, produced by either a morphine injection or footshock, was monitored (using a tail-flick test) in nonpregnant female rats. Analgesia was induced within minutes of having the rats eat on of several substances. When the substance eaten was rat placenta, both the morphine- and shock-induced types of analgesia were significantly grater than in controls that ingested other substances (or nothing). When footshock (hind-paw) was administered in conjunction with the opiate antagonist naltrexone, the analgesia produced was attenuated but detectable; in this case, placenta ingestion did not enhance the analgesia, suggesting that the effect of placenta is specific to opiate-mediated analgesia. It is possible that this enhancement of analgesia is one of the principal benefits to mammalian mothers of ingesting placenta and birth fluids (placentophagia) at delivery.
PB  - Pergamon Press
KW  - opiates
KW  -  opioids
KW  -  placentophagia
KW  -  placenta
KW  -  amniotic fluid
KW  -  delivery
KW  -  rat
KW  -  POEF
KW  -  naltrexone
KW  -  analgesia
KW  -  pain
KW  -  tail-flick test
KW  -  footshock
KW  -  afterbirth
KW  -  mammal
TI  - Placenta ingestion enhances opiate analgesia in rats.
SP  - 481
AV  - public
EP  - 486
ER  -

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