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"Amniotic-fluid ingestion by parturient rats enhances pregnancy-mediated analgesia"^^ .
"Amniotic fluid and placenta contain a substance (POEF, for Placental Opioid-Enhancing Factor) that, when ingested, enhances opioid-mediated analgesia in nonpregnant rats; ingestion of the substance by rats not experiencing opioid-mediated analgesia, however, does not produce analgesia. It is highly likely that periparturitional analgesia-enhancement is a significant benefit of ingestion of the afterbirth (placentophagia) during delivery. Here we report that prepartum ingestion of amniotic fluid (via orogastric infusion) does indeed enhance the endogenous-opioid-mediated analgesia evident at the end of pregnancy and during delivery; that the degree of enhancement is greater with 0.75 ml than with 0.25 ml, and that the prepartum enhancement of analgesia can be blocked with the opioid antagonist naloxone."^^ .
"1990" .
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"46" .
"10" .
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"Pergamon Press"^^ .
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"Life Sciences"^^ .
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"Mark B."^^ .
"Kristal"^^ .
"Mark B. Kristal"^^ .
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"P."^^ .
"Abbott"^^ .
"P. Abbott"^^ .
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"Jean M."^^ .
"DiPirro"^^ .
"Jean M. DiPirro"^^ .
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"J. C."^^ .
"Doerr"^^ .
"J. C. Doerr"^^ .
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"E.J."^^ .
"Ferguson"^^ .
"E.J. Ferguson"^^ .
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"Alexis C."^^ .
"Thompson"^^ .
"Alexis C. Thompson"^^ .
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"Amniotic-fluid ingestion by parturient rats enhances pregnancy-mediated analgesia (PDF)"^^ .
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"ls.pdf"^^ .
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"Amniotic-fluid ingestion by parturient rats enhances pregnancy-mediated analgesia (Image (PNG))"^^ .
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"preview.png"^^ .
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"HTML Summary of #5769 \n\nAmniotic-fluid ingestion by parturient rats enhances pregnancy-mediated analgesia\n\n" .
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"Psychobiology" .
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