---
abstract: "Current wisdom in classical neuroscience suggests that the only direct action of the electric field in neurons is upon voltage-gated ion channels which open and close their gates during the passage of ions. The intraneuronal biochemical activities are thought to be modulated indirectly either by entering into the cytoplasm ions that act as\r\nsecond messengers, or via linkage to the ion channels enzymes. In this paper we present a novel possibility for subneuronal processing of information by cytoskeletal microtubule tubulin tails and we show that the local electromagnetic field supports information that could\r\nbe converted into specific protein tubulin tail conformational states. Long-range collective coherent behavior of the tubulin tails could be modelled in the form of solitary waves such as sine-Gordon kinks, antikinks or breathers that propagate along the microtubule outer\r\nsurface, and the tubulin tail soliton collisions could serve as elementary computational gates that control cytoskeletal processes. The biological importance of the presented model is due to the unique biological enzymatic energase action of the tubulin tails, which is experimentally verified for controlling the sites of microtubule-associated protein\r\nattachment and the kinesin transport of post-Golgi vesicles."
altloc: []
chapter: ~
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contact_email: ~
creators_id:
  - dankomed@yahoo.com
  - ''
  - ''
creators_name:
  - family: Georgiev
    given: Danko
    honourific: ''
    lineage: ''
  - family: Papaioanou
    given: Stelios
    honourific: ''
    lineage: ''
  - family: Glazebrook
    given: James
    honourific: ''
    lineage: ''
date: 2007
date_type: published
datestamp: 2007-11-13 00:59:56
department: ~
dir: disk0/00/00/58/14
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editors_id: []
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eprint_status: archive
eprintid: 5814
fileinfo: /style/images/fileicons/application_pdf.png;/5814/1/solitons_in_brain.pdf
full_text_status: public
importid: ~
institution: ~
isbn: ~
ispublished: pub
issn: ~
item_issues_comment: []
item_issues_count: 0
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item_issues_resolved_by: []
item_issues_status: []
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keywords: 'soliton, electromagnetic field, neuron'
lastmod: 2011-03-11 08:57:00
latitude: ~
longitude: ~
metadata_visibility: show
note: ~
number: 3
pagerange: 276-291
pubdom: FALSE
publication: Neuroquantology
publisher: ~
refereed: TRUE
referencetext: ~
relation_type: []
relation_uri: []
reportno: ~
rev_number: 25
series: ~
source: ~
status_changed: 2007-11-13 00:59:56
subjects:
  - bio-phys
  - neuro-physio
succeeds: ~
suggestions: ~
sword_depositor: ~
sword_slug: ~
thesistype: ~
title: Solitonic Effects of the Local Electromagnetic Field on Neuronal Microtubules
type: journalp
userid: 3568
volume: 5
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